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Microcirculation

Kamal
Research analysis lead by Kamal Patel
All content reviewed by Examine.com Team. Published:
Last Updated:

Summary of Microcirculation

Primary Information, Benefits, Effects, and Important Facts

Scientific Information on Microcirculation


Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect microcirculation
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The mo re evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-b Centella asiatica Notable Very High See all 8 studies
There appears to be a notable improvement in microcirculation associated with oral ingestion of centella asiatica in the treatment of chronic venous insufficiency; this may extend to otherwise healthy persons, albeit at a lesser magnitude
grade-c Ginkgo biloba Minor - See study
There is a small increase in microcirculation seen in elderly persons given ginkgo biloba, extending to both periphery and the liver. Benefits seem to be time dependent and greater at day 30 relative to day 10
grade-c Hesperidin Minor - See study
While hesperidin does not influence basal (fasting) microcirculation, there is an acute increase in circulation seen with supplementation of hesperidin at the time of peak blood concentrations.
grade-c Vitamin C Minor - See study
An increase in microcirculation has been noted secondary to increased blood flow, thought to be a general property of antioxidants

All comparative evidence is now gathered in our ​A-to-Z Supplement Reference.

The evidence for each separate supplement is still freely available ​here.