Liver Damage
Research analysis led by Kamal Patel.
All content reviewed by the Examine.com Team. Published: Jun 28, 2017
Last Updated:
All content reviewed by the Examine.com Team. Published: Jun 28, 2017
Last Updated:
Summary of Liver Damage
Primary Information, Benefits, Effects, and Important Facts
Scientific Information on Liver Damage
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Human Effect Matrix
The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect liver damage
| Grade | Level of Evidence [show legend] |
|---|---|
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Robust research conducted with repeated double-blind clinical trials |
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Multiple studies where at least two are double-blind and placebo controlled |
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Single double-blind study or multiple cohort studies |
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Uncontrolled or observational studies only |
|
Level of Evidence
?
The amount of high quality evidence. The more
evidence, the more we can trust the results.
|
Outcome |
Magnitude of effect
?
The direction and size of the supplement's impact on
each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
|
Consistency of research results
?
Scientific research does not always agree. HIGH or
VERY HIGH means that most of the scientific research agrees.
|
Notes |
|---|---|---|---|---|
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Minor
|
- See all 3 studies |
Preliminary evidence showed a large decrease in fibrotic area and inflammation in the livers of persons with NAFLD given high dose (20g) betaine, but the best evidence failed to find a significant influence. An interaction is apparent, but the exact role is not known as this time.
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- | - See study |
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- | - See study |
Supplemental SAMe in a study of persons with liver damage failed to confer rehabilitative effects
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