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Lipid Peroxidation

A form of oxidation that influences lipids. In the body, it tends to reflect damage to cell membranes and is assessed by biomarkers thought to represent lipid peroxidation (MDA and TBARS).

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Human Effect Matrix

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The Human Effect Matrix looks at human studies to tell you what supplements affect Lipid Peroxidation.

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Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Supplement Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-b Notable Very High See all 11 studies
Appears to reduce biomarkers of lipid peroxidation. CoQ10 tends to be a reference drug for lipid peroxidation, and although it is more potent than other nutraceuticals it is not astounding.
grade-b Notable Very High See all 3 studies
Although there is no reference drug to compare the effects of Spirulina against, the decrease in lipid peroxidation as assessed by serum MDA is quite notable and is likely stronger than other supplements. A comparative study would be needed
grade-b Minor High See all 7 studies
Studies generally support a small-modest reduction in lipid peroxidation. More research is needed in various different health conditions.

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