Ketone Bodies
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Human Effect Matrix
The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect ketone bodies.
| Grade | Level of Evidence [show legend] |
|---|---|
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Robust research conducted with repeated double-blind clinical trials |
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Multiple studies where at least two are double-blind and placebo controlled |
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Single double-blind study or multiple cohort studies |
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Uncontrolled or observational studies only |
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Level of Evidence
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The amount of high quality evidence. The more
evidence, the more we can trust the results.
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Supplement |
Magnitude of effect
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The direction and size of the supplement's impact on
each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
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Consistency of research results
?
Scientific research does not always agree. HIGH or
VERY HIGH means that most of the scientific research agrees.
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Notes |
|---|---|---|---|---|
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Strong
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Very High See all 8 studies |
When a ketogenic diet is followed, ketone bodies will increase considerably. Ketosis is compatible with a wide range of protein intakes as long as carbohydrate intake is low, but the most ketogenic diets will be the ones low in both carbohydrates and protein.
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Minor
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- See study |
An increase in ketone bodies has been noted when fish oil is paired with a weight loss diet (relative to placebo)
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- | - See study |
No significant alterations in formation of ketone bodies, which may be due to the ketogenic BCAA (leucine) being offset by the other two glucogenic ones
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Get access to the latest nutrition research summarized
By becoming an Examine Plus member, you'll have access to all of the latest nutrition research on over 400 supplements across over 600 different health goals, outcomes, conditions, and more.
