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The Human Effect Matrix looks at human studies to tell you what supplements affect Intraocular Pressure.
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| Grade | Level of Evidence [show legend] |
|---|---|
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Robust research conducted with repeated double-blind clinical trials |
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Multiple studies where at least two are double-blind and placebo controlled |
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Single double-blind study or multiple cohort studies |
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Uncontrolled or observational studies only |
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Level of Evidence
?
The amount of high quality evidence. The more
evidence, the more we can trust the results.
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Supplement |
Magnitude of effect
?
The direction and size of the supplement's impact on
each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
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Consistency of research results
?
Scientific research does not always agree. HIGH or
VERY HIGH means that most of the scientific research agrees.
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Notes |
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- | Very High See all 3 studies |
Despite the increase in ocular blood flow associated with repeated dosing of ginkgo biloba, there does not appear to be a significant modification of intraocular blood pressure in persons with normal IOP.
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Minor
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Very High See 2 studies |
Eyedrops containing forskolin seem effective in reducing intraocular pressure (IOP), and while it seems effective orally those studies are currently confounded with the inclusion of other nutrients (and thus omitted from the HEM).
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Minor
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- See study |
Oral supplementation of melatonin (500mcg) is able to reduce intraocular pressure in otherwise healthy persons
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