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Headaches

Research analysis led by and reviewed by the Examine team.
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Human Effect Matrix

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The Human Effect Matrix looks at human studies to tell you what supplements affect Headaches.

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Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Supplement Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-a Minor Very High See all 10 studies
Headaches as a side effect of acute bronchitis are pretty much abolished with the treatment of acute bronchitis from this herb; it is doubtful that headaches from other causes aside from sickness are treated in a similar manner.
grade-c Notable Very High See 2 studies
Preliminary evidence suggests that topical application of peppermint oil is effective in reducing tension headache severity when applied at the start of the headache (can work within 15 minutes), and is comparable to 1,000mg acetominophen in potency
grade-d Notable - See study
400 mg/kg/day in children and adolescents subject to traumatic brain injury reduces headache frequency from around 90% down to near 10%.

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