HbA1c
Research analysis lead by Kamal Patel
All content reviewed by Examine.com Team. Published:
Last Updated:
All content reviewed by Examine.com Team. Published:
Last Updated:
Human Effect Matrix
The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect hba1c
| Grade | Level of Evidence [show legend] |
|---|---|
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Robust research conducted with repeated double-blind clinical trials |
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Multiple studies where at least two are double-blind and placebo controlled |
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Single double-blind study or multiple cohort studies |
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Uncontrolled or observational studies only |
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Level of Evidence
?
The amount of high quality evidence. The more
evidence, the more we can trust the results.
|
Outcome |
Magnitude of effect
?
The direction and size of the supplement's impact on
each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
|
Consistency of research results
?
Scientific research does not always agree. HIGH or
VERY HIGH means that most of the scientific research agrees.
|
Notes |
|---|---|---|---|---|
|
|
Chromium | - | Very High See all 18 studies |
Although sporadic evidence suggest improvements in HbA1c in diabetics, the entirety of the evidence does not support a reliable and significant improvement in diabetic persons.
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|
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Fish Oil | - | Moderate See all 10 studies |
Although the majority of evidence suggests absolutely no influence on HbA1c, reductions have been reported and a lone case has noted a clinically irrelevant increase of HbA1c (secondary to the increase in glucose). Practically, there is unlikely to be any large changes
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|
|
Berberine |
Strong
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Very High See all 3 studies |
The reduction of HbA1c associated with berberine, according to a meta-analysis of diabetics using 1,000-1,500mg berberine daily, was −0.72% (95% CI −0.97 to −0.47) more than placebo. This reduction appears to be one of the more significant reductions associated with dietary supplements.
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Coenzyme Q10 | |||
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Magnesium | |||
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Psyllium | |||
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Conjugated Linoleic Acid | |||
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Vitamin C | |||
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Gynostemma pentaphyllum | |||
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Spirulina | |||
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Alpha-Lipoic Acid | |||
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Citrullus colocynthis | |||
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Olive leaf extract | |||
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Panax ginseng | |||
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Salacia reticulata | |||
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Arginine | |||
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Astaxanthin | |||
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Benfotiamine | |||
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Cocoa Extract | |||
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Hesperidin | |||
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Pycnogenol | |||
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Red Clover Extract | |||
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Rose Hip | |||
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Royal Jelly | |||
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Stevia | |||
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Vitamin D | |||
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Vitamin E | |||
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Ruscus aculeatus | |||
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Aronia melanocarpa | |||
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Moringa oleifera | |||
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Nigella sativa | |||
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Safflower Oil | |||
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Tribulus terrestris | |||
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Vanadium | |||
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Yerba mate | |||
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Blueberry | |||
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Mangifera indica | |||
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Salvia hispanica | |||
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Sulbutiamine | |||
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Tetradecyl Thioacetic Acid | |||