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Research analysis lead by Kamal Patel
All content reviewed by Examine.com Team. Published:
Last Updated:

Summary of Ghrelin

Primary Information, Benefits, Effects, and Important Facts

Scientific Information on Ghrelin

Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect ghrelin
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
grade-c Marijuana Minor - See study
An increase in ghrelin has been noted with marijuana usage, likely playing a role in the increase in appetite.
grade-c Melatonin Minor Very High See 2 studies
An increase in Ghrelin appears to exist following acute supplementation of melatonin
grade-c Whey Protein Minor - See study
A decrease in Ghrelin has been observed with whey protein supplementation.
grade-c Colostrum  

All comparative evidence is now gathered in our ​A-to-Z Supplement Reference.

The evidence for each separate supplement is still freely available ​here.