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Functionality in Elderly or Injured

Supplements that improve symptoms of osteoarthritis, reduce the risk of falls, or improve muscle function in elderly persons tend to improve physical function and movement resulting in increased quality of life.

Kamal
Research analysis lead by Kamal Patel
All content reviewed by Examine.com Team. Published:
Last Updated:

Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect functionality in elderly or injured
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-b S-Adenosyl Methionine Minor Very High See all 3 studies
Somewhat of an increase in functionality of elderly persons, most likely secondary to the beneficial effects on joint health.
grade-b Dehydroepiandrosterone - High See all 3 studies
Most evidence measuring functionality in elderly persons have not found any improvement with DHEA supplementation, although it is possible that DHEA may play a role
grade-c Curcumin Notable Very High See 2 studies
In persons with osteoarthritis, the performance on a treadmill test after eight months was significantly increased (more than twice the distance covered with curcumin relative to control).
grade-c Vitamin D  
grade-c Creatine  
grade-c Kaempferia parviflora  
grade-c Krill Oil  
grade-c Phenylpiracetam  
grade-c Zinc  
grade-c Nitrate  
grade-c Oxiracetam  
grade-d Cissus quadrangularis  
grade-d Vinpocetine  

All comparative evidence is now gathered in our ​A-to-Z Supplement Reference.

The evidence for each separate supplement is still freely available ​here.