Fertility

Fertility refers to the capacity to create children, and in regards to supplementation this tends to refer to seminal parameters such as semen quality or semen motility.

This page features 7 unique references to scientific papers.


Research analysis by and verified by the Examine.com Research Team. Last updated on Apr 29, 2017.

Frequently Asked Questions

Questions and answers regarding Fertility

Q: Does ashwagandha have benefits for men?

A: Ashwagandha does appear to have benefits for men specifically. These tend to centralize around testicular health and fertility while the antistress effects affect both sexes.

Read full answer to "Does ashwagandha have benefits for men?"


Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect fertility

Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
Inositol
All comparative evidence is now gathered in our ​Supplement Goals Reference.
The evidence for each separate supplement is still freely available ​here.
Dehydroepiandrosterone  
Zinc  
Astaxanthin  
D-Aspartic Acid  
Coenzyme Q10  

Scientific Support & Reference Citations

Via HEM and FAQ:

  1. Mahdi AA, et al. Withania somnifera Improves Semen Quality in Stress-Related Male Fertility. Evid Based Complement Alternat Med. (2009)
  2. Gupta A, et al. Efficacy of Withania somnifera on seminal plasma metabolites of infertile males: A proton NMR study at 800MHz. J Ethnopharmacol. (2013)
  3. Mayor S. Testosterone may improve sexual function and mood in older men with low levels. BMJ. (2016)
  4. Andrade C, et al. A double-blind, placebo-controlled evaluation of the anxiolytic efficacy ff an ethanolic extract of withania somnifera. Indian J Psychiatry. (2000)
  5. Chandrasekhar K, Kapoor J, Anishetty S. A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults. Indian J Psychol Med. (2012)
  6. Agnihotri AP, et al. Effects of Withania somnifera in patients of schizophrenia: A randomized, double blind, placebo controlled pilot trial study. Indian J Pharmacol. (2013)
  7. Raut AA, et al. Exploratory study to evaluate tolerability, safety, and activity of Ashwagandha (Withania somnifera) in healthy volunteers. J Ayurveda Integr Med. (2012)