Fatigue (non-anemic)
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Human Effect Matrix
The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect fatigue (non-anemic).
| Grade | Level of Evidence [show legend] |
|---|---|
|
Robust research conducted with repeated double-blind clinical trials |
|
Multiple studies where at least two are double-blind and placebo controlled |
|
Single double-blind study or multiple cohort studies |
|
Uncontrolled or observational studies only |
|
Level of Evidence
?
The amount of high quality evidence. The more
evidence, the more we can trust the results.
|
Supplement |
Magnitude of effect
?
The direction and size of the supplement's impact on
each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
|
Consistency of research results
?
Scientific research does not always agree. HIGH or
VERY HIGH means that most of the scientific research agrees.
|
Notes |
|---|---|---|---|---|
|
|
Minor
|
Very High See all 7 studies |
In people without anemia, but who have iron deficiency or low ferritin levels, increasing iron stores through oral or intravenous supplementation can reduce fatigue somewhat. It's unclear if the average person with iron levels traditionally considered to be sufficient can benefit from increased iron intake in this regard, though what research we have suggests that it's unlikely.
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