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Fatigue is a decrease in energy that lowers motivation and mental and physical performance. Some supplements are stimulants; they provide a temporary boost. Others may help by improving sleep (if bad sleep is a cause) or energy metabolism (either directly or by affecting hormones).

Our evidence-based analysis on fatigue features 2 unique references to scientific papers.

Research analysis led by and reviewed by the Examine team.
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  1. Li-Ng M, Kennedy L. Adrenal Insufficiency. J Surg Oncol. (2012)
  2. Salvatori R. Adrenal insufficiency. JAMA. (2005)