Fatigue

A chronic lack of motivation and 'energy'/'vitality', Fatigue can be acutely countered by stimulants (not advisable for the long term) or may be slowly mended by other compounds like Reishi or CoQ10.

Our evidence-based analysis features 2 unique references to scientific papers.


Research analysis by and verified by the Examine.com Research Team. Last updated on Apr 29, 2017.

Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect fatigue

Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
Rhodiola Rosea
All comparative evidence is now gathered in our ​A-to-Z Supplement Reference.
The evidence for each separate supplement is still freely available ​here.
Creatine  
Modafinil  
Beta-Alanine  
Branched Chain Amino Acids  
Coenzyme Q10  
L-Carnitine  
Pelargonium sidoides  
Trimethylglycine  
Citrulline  
Colostrum  
Alanylglutamine  
Ashwagandha  
Caffeine  
Coleus forskohlii  
Curcumin  
Ganoderma lucidum  
Glycine  
Ornithine  
Phosphatidylserine  
Pyruvate  
Valeriana officinalis  
Vitamin C  
7-Keto DHEA  
Choline  
Cocoa Extract  
Fish Oil  
HMB  
L-Tyrosine  
Marijuana  
Methylsulfonylmethane  
Quercetin  
Resveratrol  
Tribulus terrestris  
Melissa officinalis  
Pyrroloquinoline quinone  
D-Ribose  
Phenylpiracetam  
Spirulina  
Vitamin B12  
Vitex agnus castus  

Cite this page

"Fatigue," Examine.com, published on 6 February 2013, last updated on 29 April 2017, https://examine.com/topics/fatigue/