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Fat Mass

Fat Mass is a term for adipose tissue, the scientific name for any body fat you carry on you as a form of energy storage. Although not unhealth per se, many people termed obese carry too much body fat and a reduction of fat mass is seen as healthy and desirable.

Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect fat mass
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
grade-a Green Tea Catechins Minor Very High See all 6 studies
There appears to be a fat reducing effect associated with green tea, but it is minor and unreliable
grade-a Chromium - Very High See all 11 studies
There doesn't appear to be a significant nor reliable reduction in fat mass even in diabetics given chromium supplementation according to the literature.
grade-a Conjugated Linoleic Acid - Moderate See all 20 studies
Evidence is too unreliable to conclude an inhernet effect of CLA on fat mass. There may be a context-dependent reduction in body fat and explanation for the observed variability, but at this moment in time too much evidence concludes no effect
grade-b Ephedrine  
grade-b HMB  
grade-b L-Carnitine  
grade-b Vitamin D  
grade-b Whey Protein  
grade-b Colostrum  
grade-b Creatine  
grade-b Dehydroepiandrosterone  
grade-b Pyruvate  
grade-b Trimethylglycine  
grade-c Clenbuterol  
grade-c Yohimbine  
grade-c 7-Keto DHEA  
grade-c Arginine  
grade-c Beta-Alanine  
grade-c Coleus forskohlii  
grade-c Fenugreek  
grade-c Grapefruit  
grade-c Green Coffee Extract  
grade-c Irvingia gabonensis  
grade-c Arachidonic acid  
grade-c Chlorella  
grade-c D-Aspartic Acid  
grade-c Fish Oil  
grade-c Glutamine  
grade-c Hoodia gordonii  
grade-c Leucic Acid  
grade-c Leucine  
grade-c Licorice  
grade-c Punicic Acid  
grade-c Tauroursodeoxycholic Acid  
grade-c Tribulus terrestris  
grade-c Ursolic Acid  
grade-c Vitamin B3 (Niacin)  
grade-c Vitamin C  
grade-d Ashwagandha  
grade-d Medium-chain triglycerides  
grade-d Cocoa Extract  
grade-d Eurycoma Longifolia Jack  
grade-d Mangifera indica  
grade-d Safflower Oil  
grade-d Zinc  

All comparative evidence is now gathered in our ​A-to-Z Supplement Reference.

The evidence for each separate supplement is still freely available ​here.