Quick Navigation

Endothelin-1

Kamal
Research analysis lead by Kamal Patel
All content reviewed by Examine.com Team.
Published:
Last Updated:

Summary of Endothelin-1

Primary Information, Benefits, Effects, and Important Facts

Scientific Information on Endothelin-1


Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect endothelin-1
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The mo re evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-c Arginine Minor - See study
A decrease in concentrations of endothelin-1 has been noted with supplemental L-arginine
grade-c Pycnogenol - - See 2 studies
grade-c Vitamin E - - See study
Endothelin-1 has failed to be influenced with supplementation of vitamin E in diabetics.

All comparative evidence is now gathered in our ​A-to-Z Supplement Reference.

The evidence for each separate supplement is still freely available ​here.