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Endothelial Function

Endothelial function (vasoreactivity) tends to refer to the reactivity of blood vessels to dilate or contract upon demand, and is associated with blood flow and arterial calcification. Improved vasoreactivity is associated with reduced risk for cardiovascular incidents.

Kamal Patel
Research analysis led by .
Reviewed by
Examine.com Team
Last Updated:

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Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect endothelial function.
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Supplement Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-b
Coenzyme Q10
Minor Very High See all 5 studies
The effective size does not appear to be overly large, but CoQ10 is associated with a protective effect on blood flow and endothelial function in persons with otherwise impaired function.
grade-b
Fish Oil
Minor Very High See all 4 studies
There appears to be a slight increase in vascular reactivity and blood vessel responsiveness that may be independent of both blood flow alterations and blood pressure
grade-c
Arginine
Minor Moderate See 2 studies
Unreliable improvements in endothelial function, notably in persons with impaired glucose tolerance/type II diabetes, associated with the supposed increase in nitric oxide

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grade-c
Panax ginseng
 
grade-c
Vitamin D
 
grade-d
Grape juice
 
grade-d
Vitamin C
 
grade-d
Curcumin
 

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This page is regularly updated, to include the most recently available clinical trial evidence.

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This page features 0 references. All factual claims are followed by specifically-applicable references. Click here to see the full set of research information and references for Endothelial Function.

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