Dopamine
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Human Effect Matrix
The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect dopamine.
| Grade | Level of Evidence [show legend] |
|---|---|
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Robust research conducted with repeated double-blind clinical trials |
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Multiple studies where at least two are double-blind and placebo controlled |
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Single double-blind study or multiple cohort studies |
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Uncontrolled or observational studies only |
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Level of Evidence
?
The amount of high quality evidence. The more
evidence, the more we can trust the results.
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Supplement |
Magnitude of effect
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The direction and size of the supplement's impact on
each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
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Consistency of research results
?
Scientific research does not always agree. HIGH or
VERY HIGH means that most of the scientific research agrees.
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Notes |
|---|---|---|---|---|
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Minor
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- See study |
Serum dopamine has been noted to be slightly reduced (37%) during waking at rest, but this decrease was eliminated upon walking
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Minor
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- See study |
The reduction in dopamine seen in infertility seems to be reversed with L-DOPA ingestion; theoretically L-DOPA ingestion should unilaterally increase dopamine
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- | - See study |
Similar to the other catecholamines (adrenaline and noradrenaline), serum dopamine does not appear to be altered with supplemental BCAAs.
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Get access to the latest nutrition research
By becoming an Examine Plus member, you'll have access to all of the latest nutrition research on over 300 supplements across over 500 different health goals, outcomes, conditions, and more.
Frequently Asked Questions and Articles on Dopamine
Do herbal aphrodisiacs work?
It depends on the product touted to be an aphrodisiac, but some of them do apparently increase sexual desire; it is a relatively under-researched topic though, and we don't know why they increase sexuality.
Does ejaculation affect testosterone levels?
Ejaculation results in changes in prolactin (increase) and dopamine (temporary decrease), but does not result in changes in testosterone. Although prolactin and dopamine are both involved with testosterone, they do not appear to influence testosterone levels acutely.
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