DNA Methylation
Research analysis led by Kamal Patel.
All content reviewed by the Examine.com Team. Published:
Last Updated:
All content reviewed by the Examine.com Team. Published:
Last Updated:
Summary of DNA Methylation
Primary Information, Benefits, Effects, and Important Facts
Scientific Information on DNA Methylation
Human Effect Matrix
The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect dna methylation
| Grade | Level of Evidence [show legend] |
|---|---|
|
Robust research conducted with repeated double-blind clinical trials |
|
Multiple studies where at least two are double-blind and placebo controlled |
|
Single double-blind study or multiple cohort studies |
|
Uncontrolled or observational studies only |
|
Level of Evidence
?
The amount of high quality evidence. The more
evidence, the more we can trust the results.
|
Outcome |
Magnitude of effect
?
The direction and size of the supplement's impact on
each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
|
Consistency of research results
?
Scientific research does not always agree. HIGH or
VERY HIGH means that most of the scientific research agrees.
|
Notes |
|---|---|---|---|---|
|
|
Creatine |
Minor
|
- See study |
The effect of creatine supplementation on DNA methylation cannot be properly assessed due to a lack of comparisons with other agents.
|
|
|
Resveratrol |
Minor
|
- See study |
A decrease in DNA methylation rates has been noted
|