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Coronary artery disease (CAD)

Coronary artery disease (CAD) is the most common type of CVD in the United States. It is caused by atherosclerosis.

Kamal Patel
Research analysis led by and reviewed by the Examine team.
Last Updated:
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Summary of Coronary artery disease (CAD)

Scientific Information on Coronary Heart Disease Risk

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Human Effect Matrix

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The Human Effect Matrix looks at human studies to tell you what supplements affect Coronary artery disease (CAD).

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Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Supplement Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-b
Vitamin B3 (Niacin)
Minor - See study
One meta-analysis found a decrease in the risk of developing coronary heart disease when compared to control.
grade-d
Black Cohosh
Minor - See study
A slightly increased chance of heart disease was said to occur in one study pairing black cohosh with exercise, and an increased risk was also determined in control but not in black cohosh in isolation.

Things to Note

Also Known As

coronary heart disease, ischemic heart disease

This page is regularly updated, to include the most recently available clinical trial evidence.

Each member of our research team is required to have no conflicts of interest, including with supplement manufacturers, food companies, and industry funders. The team includes nutrition researchers, registered dietitians, physicians, and pharmacists. We have a strict editorial process.

This page features 0 references. All factual claims are followed by specifically-applicable references. Click here to see the full set of research information and references for Coronary artery disease (CAD).

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