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Constipation

Conspitation is the state where intestinal motility decreases to such a degree that the persons can no longer easily defecate and has intestinal pain. In this instance, some laxative compounds are recommended.

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Human Effect Matrix

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The Human Effect Matrix looks at human studies to tell you what supplements affect Constipation.

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Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Supplement Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-b Strong Very High See all 6 studies
Due to the strong laxative effect, constipation is greatly reduced with supplemental Senna Alexandria. Has been noted effective against regular, postpartum, and opioid-induced constipation and appears to not require a context-specific cause of constipation (ie. reliable) but appears to be associated with more cramping than placebo.
grade-c Minor - See study
A decrease in the symptoms of constipation has been seen with the water extract of jujubes; which may apply to fruit consumption but may not apply to isolated supplements (due to the polysaccharides being the active ingredients)
grade-c - - See 2 studies
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