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Constipation

Conspitation is the state where intestinal motility decreases to such a degree that the persons can no longer easily defecate and has intestinal pain. In this instance, some laxative compounds are recommended.

Research analysis led by Kamal Patel.
All content reviewed by the Examine.com Team. Published:
Last Updated:

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Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect constipation
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-b Strong Very High See all 6 studies
Due to the strong laxative effect, constipation is greatly reduced with supplemental Senna Alexandria. Has been noted effective against regular, postpartum, and opioid-induced constipation and appears to not require a context-specific cause of constipation (ie. reliable) but appears to be associated with more cramping than placebo.
grade-c Minor - See study
A decrease in the symptoms of constipation has been seen with the water extract of jujubes; which may apply to fruit consumption but may not apply to isolated supplements (due to the polysaccharides being the active ingredients)
grade-c - - See 2 studies

All comparative evidence is now gathered in our ​A-to-Z Supplement Reference.

The evidence for each separate supplement is still freely available ​here.