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The Human Effect Matrix looks at human studies to tell you what supplements affect Constipation.
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| Grade | Level of Evidence [show legend] |
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Robust research conducted with repeated double-blind clinical trials |
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Multiple studies where at least two are double-blind and placebo controlled |
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Single double-blind study or multiple cohort studies |
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Uncontrolled or observational studies only |
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Level of Evidence
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The amount of high quality evidence. The more
evidence, the more we can trust the results.
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Supplement |
Magnitude of effect
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The direction and size of the supplement's impact on
each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
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Consistency of research results
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Scientific research does not always agree. HIGH or
VERY HIGH means that most of the scientific research agrees.
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Notes |
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Strong
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Very High See all 6 studies |
Due to the strong laxative effect, constipation is greatly reduced with supplemental Senna Alexandria. Has been noted effective against regular, postpartum, and opioid-induced constipation and appears to not require a context-specific cause of constipation (ie. reliable) but appears to be associated with more cramping than placebo.
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Minor
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- See study |
A decrease in the symptoms of constipation has been seen with the water extract of jujubes; which may apply to fruit consumption but may not apply to isolated supplements (due to the polysaccharides being the active ingredients)
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- | - See 2 studies |
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