Constipation
Research analysis led by Kamal Patel.
All content reviewed by the Examine.com Team. Published: Jul 5, 2013
Last Updated:
All content reviewed by the Examine.com Team. Published: Jul 5, 2013
Last Updated:
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Human Effect Matrix
The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect constipation
| Grade | Level of Evidence [show legend] |
|---|---|
|
Robust research conducted with repeated double-blind clinical trials |
|
Multiple studies where at least two are double-blind and placebo controlled |
|
Single double-blind study or multiple cohort studies |
|
Uncontrolled or observational studies only |
|
Level of Evidence
?
The amount of high quality evidence. The more
evidence, the more we can trust the results.
|
Outcome |
Magnitude of effect
?
The direction and size of the supplement's impact on
each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
|
Consistency of research results
?
Scientific research does not always agree. HIGH or
VERY HIGH means that most of the scientific research agrees.
|
Notes |
|---|---|---|---|---|
|
|
Strong
|
Very High See all 6 studies |
Due to the strong laxative effect, constipation is greatly reduced with supplemental Senna Alexandria. Has been noted effective against regular, postpartum, and opioid-induced constipation and appears to not require a context-specific cause of constipation (ie. reliable) but appears to be associated with more cramping than placebo.
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|
|
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Minor
|
- See study |
A decrease in the symptoms of constipation has been seen with the water extract of jujubes; which may apply to fruit consumption but may not apply to isolated supplements (due to the polysaccharides being the active ingredients)
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|
|
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- | - See 2 studies |
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