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Colorectal Cancer Risk

Some dietary supplements are thought to reduce the risk of colonic cancer, and this is assessed by either epidemiological research showing a relationship or studies that note how supplementation can reduce a known biomarker of colon cancer.

Research analysis led by Kamal Patel.
All content reviewed by the Examine.com Team. Published:
Last Updated:

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Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect colorectal cancer risk
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-b Notable - See study
The association between serum Vitamin D at 37ng/mL and colorectal cancer is is approximately a halving of risk according to one meta-analysis, which is a notable risk reduction
grade-c Minor Very High See 2 studies
Appears to be associated with a reduced risk for colon cancer
grade-d Notable - See study
More than a halving of the risk of colorectal cancer has been noted with panax ginseng daily ingestion

All comparative evidence is now gathered in our ​A-to-Z Supplement Reference.

The evidence for each separate supplement is still freely available ​here.