The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect cognition.
| Grade | Level of Evidence [show legend] |
|---|---|
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Robust research conducted with repeated double-blind clinical trials |
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Multiple studies where at least two are double-blind and placebo controlled |
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Single double-blind study or multiple cohort studies |
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Uncontrolled or observational studies only |
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Level of Evidence
?
The amount of high quality evidence. The more
evidence, the more we can trust the results.
|
Supplement |
Magnitude of effect
?
The direction and size of the supplement's impact on
each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
|
Consistency of research results
?
Scientific research does not always agree. HIGH or
VERY HIGH means that most of the scientific research agrees.
|
Notes |
|---|---|---|---|---|
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Notable
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Very High See all 4 studies |
Notably effective assuming fatigue is being reduced. There is insufficient evidence to evaluate rhodiola's effects on cognition without the fatigue reduction aspect
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Minor
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High See all 3 studies |
There may be an improvement in cognitive performance secondary to reducing symptoms of schizophrenia, and while there is mechanistic plausibility that this can also work in normal controls it has not yet been demonstrated
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Minor
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High See all 7 studies |
Other parameters of cognition are differentially influenced by ginkgo, as facial recognition in those with dementia has noted improvement yet trip planning in middle-aged persons is unaffected.
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