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Cerebral Blood Flow

The amount of blood, and thus oxygen, that is delivered to the brain. Compounds can enhance cerebral blood flow by either fixing problems in unhealthy persons (fish oil) or outright increase flow (Resveratrol, Chocamine). Does not increase cognition per se, but may augment nootropics.

Kamal
Research analysis lead by Kamal Patel
All content reviewed by Examine.com Team. Published:
Last Updated:

Things To Know & Note

Also Known As

Neural Blood Flow

Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect cerebral blood flow
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-b Marijuana
Minor
- See all 3 studies
Both increases and decreases seem to have been reported over the whole brain, and it seems that in people who do not experience orthostatic hypotension from marijuana it is generally an increase; blood flow to the ACC in particular is increased following THC, but this becomes a decrease during tolerance.
grade-c Cocoa Extract Minor - See study
Cerebral blood flow during cognitive testing in youth can be increased from 170mg cocoa flavanols, although may not coexist with increases in cognition.
grade-c Fish Oil Minor - See study
Appears to improve cerebral blood flow and volume in persons with low dietary fish intake
grade-c Ginkgo biloba  
grade-c Green Tea Catechins  
grade-c Polypodium leucotomos  
grade-c Resveratrol  
grade-c Melatonin  
grade-d Yohimbine  

All comparative evidence is now gathered in our ​A-to-Z Supplement Reference.

The evidence for each separate supplement is still freely available ​here.