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Calmness is a similar parameter to relaxation, although they have differnet rating scales at time. Both calmness and relaxation are associated with slightly sedative and anxiolytic compounds.

Research analysis led by Kamal Patel.
All content reviewed by the Examine.com Team. Published:
Last Updated:

Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect calmness
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
grade-c Melissa officinalis Notable Very High See 2 studies
An increase in self-reported ratings of 'calmness' appears to exist following ingestion of lemon balm single doses
grade-c Centella asiatica Minor Very High See 2 studies
A reduction in fear and anxiety responses to an acute startle response (indicative of less responsiveness to alerting stimuli and more calmness) has been noted with this plant extract
grade-c Cocoa Extract Minor - See study
One study using relatively high doses of cocoa flavanols (500mg) found an increased rate of calmness and well being when compared to placebo in otherwise healthy subjects.
grade-c Ginkgo biloba  
grade-c Panax ginseng  
grade-c Rose Essential Oil  
grade-c Lavender  
grade-c Modafinil  
grade-d Peppermint  

All comparative evidence is now gathered in our ​A-to-Z Supplement Reference.

The evidence for each separate supplement is still freely available ​here.