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Breast Tenderness

Breast tenderness refers to the actual physical tenderness of breast tissue, usually associated with a small amount of pain. Breast tenderness tends to be a symptom of PMS or menopause, and supplements that reduce those symptoms help with breast tenderness.

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Human Effect Matrix

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The Human Effect Matrix looks at human studies to tell you what supplements affect Breast Tenderness.

Full details on all Breast Tenderness supplements are available to Examine Plus members.
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Supplement Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-b Notable Very High See all 5 studies
The increase in breast tenderness during PMS is ameliorated with vitex supplementation; the degree of benefit correlating with general reductions in PMS symptoms. Notable as supplements catering to breast tenderness are rare.
grade-c Minor - See study
Secondary to reducing symptoms of PMS, a reduction in breast tenderness has been reported
grade-c Minor - See study
A decrease in breast tenderness and soreness has been noted with serrapeptase treatment in one study.

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