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Breast Tenderness

Breast tenderness refers to the actual physical tenderness of breast tissue, usually associated with a small amount of pain. Breast tenderness tends to be a symptom of PMS or menopause, and supplements that reduce those symptoms help with breast tenderness.

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Human Effect Matrix

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The Human Effect Matrix looks at human studies to tell you what supplements affect Breast Tenderness.

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Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Supplement Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-b Notable Very High See all 5 studies
The increase in breast tenderness during PMS is ameliorated with vitex supplementation; the degree of benefit correlating with general reductions in PMS symptoms. Notable as supplements catering to breast tenderness are rare.
grade-c Minor - See study
Secondary to reducing symptoms of PMS, a reduction in breast tenderness has been reported
grade-c Minor - See study
A decrease in breast tenderness and soreness has been noted with serrapeptase treatment in one study.
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