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Breast Tenderness

Breast tenderness refers to the actual physical tenderness of breast tissue, usually associated with a small amount of pain. Breast tenderness tends to be a symptom of PMS or menopause, and supplements that reduce those symptoms help with breast tenderness.

Kamal Patel
Research analysis led by .
Reviewed by
Examine.com Team
Last Updated:

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Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect breast tenderness.
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Supplement Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-b
Vitex agnus-castus
Notable Very High See all 5 studies
The increase in breast tenderness during PMS is ameliorated with vitex supplementation; the degree of benefit correlating with general reductions in PMS symptoms. Notable as supplements catering to breast tenderness are rare.
grade-c
Krill Oil
Minor - See study
Secondary to reducing symptoms of PMS, a reduction in breast tenderness has been reported
grade-c
Serrapeptase
Minor - See study
A decrease in breast tenderness and soreness has been noted with serrapeptase treatment in one study.

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grade-d
Vitamin B₆
 
grade-d
Fish Oil
 
grade-d
Vitamin E
 

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This page is regularly updated, to include the most recently available clinical trial evidence.

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This page features 0 references. All factual claims are followed by specifically-applicable references. Click here to see the full set of research information and references for Breast Tenderness.

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