Breast Tenderness
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Human Effect Matrix
The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect breast tenderness.
| Grade | Level of Evidence [show legend] |
|---|---|
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Robust research conducted with repeated double-blind clinical trials |
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Multiple studies where at least two are double-blind and placebo controlled |
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Single double-blind study or multiple cohort studies |
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Uncontrolled or observational studies only |
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Level of Evidence
?
The amount of high quality evidence. The more
evidence, the more we can trust the results.
|
Supplement |
Magnitude of effect
?
The direction and size of the supplement's impact on
each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
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Consistency of research results
?
Scientific research does not always agree. HIGH or
VERY HIGH means that most of the scientific research agrees.
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Notes |
|---|---|---|---|---|
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Notable
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Very High See all 5 studies |
The increase in breast tenderness during PMS is ameliorated with vitex supplementation; the degree of benefit correlating with general reductions in PMS symptoms. Notable as supplements catering to breast tenderness are rare.
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Minor
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- See study |
Secondary to reducing symptoms of PMS, a reduction in breast tenderness has been reported
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Minor
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- See study |
A decrease in breast tenderness and soreness has been noted with serrapeptase treatment in one study.
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