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Blood Acidity

Blood Acidity is a way of referring to the pH of the blood, and while the blood tends to be resiliant to large changes some supplements may slightly influence pH. Overly large deviations in pH are associated with metabolic abnormalities.

Research analysis led by Kamal Patel.
All content reviewed by the Examine.com Team. Published:
Last Updated:

Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect blood acidity
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
grade-a Sodium Bicarbonate Notable Very High See all 46 studies
Although the magnitude of decrease is somewhat minor, this is due to blood pH being highly regulated in the body. acidity appears to be reliably reduced following supplementation of 300mg/kg sodium bicarbonate
grade-c Colostrum - Moderate See 2 studies
While one study noted an increase in buffering capacity of the blood (reduction in acidity), this observation failed to be replicated in another study and both failed to find an ergogenic effect thought to occur after such an increase in buffer capacity.

All comparative evidence is now gathered in our ​A-to-Z Supplement Reference.

The evidence for each separate supplement is still freely available ​here.