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Apolipoprotein A

Apolipoprotein A is the apolipoprotein for HDL cholesterol, and increasing its concentrations promotes flux of fatty acids and molecules that are carried on lipoproteins away from peripheral tissue and towards the liver.

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Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect apolipoprotein a
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-b - High See all 4 studies
A large decrease has been noted in one study in overweight postmenopausal women, although three other studies failed to replicate this decrease.
grade-c Minor - See study
In high risk individuals, the reduction has been noted to be 23.4+/-7.9%
grade-c Minor - See study
An increase in Apolipoprotein A1 has been noted with supplementation of betaine relative to placebo in otherwise healthy persons.

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