Quick Navigation

All-Cause Mortality

Research analysis led by .
Reviewed by
Examine.com Team
Last Updated:

Summary of All-Cause Mortality

Scientific Information on All-Cause Mortality

Easily stay on top of the latest nutrition research

Become an Examine Member to get access to the latest research. Get 150+ studies summarized for you across 25 different categories every month.

Members also have access to the Examine Study Database of 400+ supplements and their effects on 600+ health outcomes, as well as in-depth research analyses. Understand the whole body of nutrition and supplement evidence at a glance.

Get instant access — start your free 14-day trial

Already a Member? Click here to log in.


Human Effect Matrix

Unlocked for Examine Members

Easily stay on top of the latest nutrition research

Become an Examine Member to get access to the latest research. Get 150+ studies summarized for you across 25 different categories every month.

Members also have access to the Examine Study Database of 400+ supplements and their effects on 600+ health outcomes, as well as in-depth research analyses. Understand the whole body of nutrition and supplement evidence at a glance.

Get instant access — start your free 14-day trial

Already a Member? Click here to log in.


The Human Effect Matrix looks at human studies to tell you what supplements affect All-Cause Mortality.

Unlock the full Study Database with an Examine Membership. Get a 14-day free trial.
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Supplement Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-a
Minor
- See all 7 studies
Minor increases in all cause mortality have been noted in mostly unhealthy cohorts with doses of vitamin E above 400IU (alpha-tocopherol) whereas lower doses exert a mild protective effect in the same cohorts. The magnitude is approximately 33-34 deaths per 10,000 subjects (both for the increase in mortality seen with vitamin E multinutrient supplements and the decrease seen with vitamin E alone), and it is unsure how this information applies to otherwise healthy persons.
grade-c Minor Very High See 2 studies
Cohorts of people with higher serum Vitamin D appear to die less frequently than cohorts with less serum Vitamin D; this may be heavily influenced by reducing falls in the elderly (reduction of falls and subsequent hospitalizations reducing death rates)

Stay on top of the latest research

To unlock the full archives of our Study Database and research analyses, become an Examine Member today.

Start your 14-day free trial