Quick Navigation

All-Cause Mortality

Research analysis led by .
Reviewed by
Examine.com Team
Last Updated:

Summary of All-Cause Mortality

Scientific Information on All-Cause Mortality

Get the latest information on 400+ supplements and their effects on 600+ health conditions & outcomes.

By becoming an Examine Plus member, you'll have access to all of the latest nutrition research. Quickly and easily look up scientific research on over 400 supplements across over 600 different health goals, outcomes, conditions, and more.

Human Effect Matrix

Unlocked for Examine Plus members

The Human Effect Matrix looks at human studies to tell you what supplements affect All-Cause Mortality.

Full details on all All-Cause Mortality supplements are available to Examine Plus members.
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Supplement Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-a
Minor
- See all 7 studies
Minor increases in all cause mortality have been noted in mostly unhealthy cohorts with doses of vitamin E above 400IU (alpha-tocopherol) whereas lower doses exert a mild protective effect in the same cohorts. The magnitude is approximately 33-34 deaths per 10,000 subjects (both for the increase in mortality seen with vitamin E multinutrient supplements and the decrease seen with vitamin E alone), and it is unsure how this information applies to otherwise healthy persons.
grade-c Minor Very High See 2 studies
Cohorts of people with higher serum Vitamin D appear to die less frequently than cohorts with less serum Vitamin D; this may be heavily influenced by reducing falls in the elderly (reduction of falls and subsequent hospitalizations reducing death rates)

Become an Examine Plus member to access the latest nutrition research on over 400 supplements across over 600 different health goals, outcomes, conditions, and more.

Becoming an Examine Plus member not only unlocks the Human Effect Matrix for supplements, but also all health topics on Examine.com. We neatly summarize all the latest research so you can make the best decisions for your health based on what's accurate and not out-dated information.