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Alcohol Dependence

Research analysis led by and reviewed by the Examine team.
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Summary of Alcohol Dependence

Scientific Information on Alcohol Dependence

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Human Effect Matrix

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The Human Effect Matrix looks at human studies to tell you what supplements affect Alcohol Dependence.

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Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Supplement Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-c Minor - See study
A reduced rate of relapse and alcohol cravings was noted with ALCAR ingestion relative to placebo
grade-c Minor - See study
Alcohol dependence, particularly the impulsivity thereof, appears to be slightly reduced with modafinil administration
grade-c Minor - See study
Injections of yohimbine have been noted to increase cravings for alcohol, which although not demonstrated with oral intake is thought to be related to the reduction in inhibition

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