Quick Navigation


Research analysis led by .
Reviewed by
Examine.com Team
Last Updated:

Summary of 8-isoPGF2a

Primary Information, Benefits, Effects, and Important Facts

Scientific Information on 8-isoPGF2a

Improve your health with the latest information on 400+ supplements and their effects on 600+ health outcomes.

By becoming an Examine Plus member, you'll have access to all of the latest nutrition research. Quickly and easily look up scientific research on over 400 supplements across over 600 different health goals, outcomes, conditions, and more.

Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect 8-isopgf2a.
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Supplement Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
grade-b Minor Moderate See all 4 studies
This biomarker of inflammation has been noted to be reduced in two studies where the subjects were prooxidative at rest (PAD and smokers), with no influence in other studies of otherwise healthy subjects.
grade-c Minor Very High See all 3 studies
8-isoPGF(2)a is normally a biomarker of lipid peroxidation, but CLA may be causing a false positive (as fatty acids are known to interact with the enzymes in question and other markers of lipid peroxidation are unchanged).
grade-c - - See study
Urinary 8-isoPGF2α is unchanged with prolonged quercetin supplementation.