MitoQ
•Last Updated: September 28 2022
MitoQ (mitoquinone mesylate) is a derivative of CoQ10 believed to play a role in mitochondrial function.
MitoQ is most often used for
Last Updated: September 28 2022
Research feed
1.^Murphy MP, Smith RATargeting antioxidants to mitochondria by conjugation to lipophilic cationsAnnu Rev Pharmacol Toxicol.(2007)
3.^Interactions of Mitochondria-targeted and Untargeted Ubiquinones with the Mitochondrial Respiratory Chain and Reactive Oxygen Species.()
4.^James AM, Cochemé HM, Smith RA, Murphy MPInteractions of mitochondria-targeted and untargeted ubiquinones with the mitochondrial respiratory chain and reactive oxygen species. Implications for the use of exogenous ubiquinones as therapies and experimental toolsJ Biol Chem.(2005 Jun 3)
5.^Rodriguez-Cuenca S, Cochemé HM, Logan A, Abakumova I, Prime TA, Rose C, Vidal-Puig A, Smith AC, Rubinsztein DC, Fearnley IM, Jones BA, Pope S, Heales SJ, Lam BY, Neogi SG, McFarlane I, James AM, Smith RA, Murphy MPConsequences of long-term oral administration of the mitochondria-targeted antioxidant MitoQ to wild-type miceFree Radic Biol Med.(2010 Jan 1)
6.^Hoyer SOxidative metabolism deficiencies in brains of patients with Alzheimer's diseaseActa Neurol Scand Suppl.(1996)
7.^Hirai K, Aliev G, Nunomura A, Fujioka H, Russell RL, Atwood CS, Johnson AB, Kress Y, Vinters HV, Tabaton M, Shimohama S, Cash AD, Siedlak SL, Harris PL, Jones PK, Petersen RB, Perry G, Smith MAMitochondrial abnormalities in Alzheimer's diseaseJ Neurosci.(2001 May 1)
8.^Manczak M, Mao P, Calkins MJ, Cornea A, Reddy AP, Murphy MP, Szeto HH, Park B, Reddy PHMitochondria-targeted antioxidants protect against amyloid-beta toxicity in Alzheimer's disease neuronsJ Alzheimers Dis.(2010)
9.^McManus MJ, Murphy MP, Franklin JLThe mitochondria-targeted antioxidant MitoQ prevents loss of spatial memory retention and early neuropathology in a transgenic mouse model of Alzheimer's diseaseJ Neurosci.(2011 Nov 2)
Primary Use
Secondary Use