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Lactase enzyme

If you can't digest the lactose in dairy (Lactose intolerance), you can either supplement with lactase enzyme pills or consume dairy that's predigested with the lactase enzyme.

Our evidence-based analysis on lactase enzyme features 15 unique references to scientific papers.

Research analysis led by and reviewed by the Examine team.
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  1. ^ Nagy L, et al. Efficacy testing of beta-galactosidase with H2 breath test in patients with carbohydrate malabsorption. Acta Med Hung. (1987)
  2. ^ Gupta R, Gupta S. Dietary management of lactose intolerance--lactase treated milk versus soya milk. Indian J Med Sci. (1993)
  3. ^ Lin MY, et al. Comparative effects of exogenous lactase (beta-galactosidase) preparations on in vivo lactose digestion. Dig Dis Sci. (1993)
  4. ^ Medow MS, et al. Beta-galactosidase tablets in the treatment of lactose intolerance in pediatrics. Am J Dis Child. (1990)
  5. ^ Sanders SW, Tolman KG, Reitberg DP. Effect of a single dose of lactase on symptoms and expired hydrogen after lactose challenge in lactose-intolerant subjects. Clin Pharm. (1992)
  6. Abaturov AY, Stepanov YM, Nikulina AA. Treatment of lactase deficiency in children's obesity with genotype c/c 13910 of lactase gene. Wiad Lek. (2019)
  7. Ibba I, et al. Effects of exogenous lactase administration on hydrogen breath excretion and intestinal symptoms in patients presenting lactose malabsorption and intolerance. Biomed Res Int. (2014)
  8. de Vrese M, et al. A combination of acid lactase from Aspergillus oryzae and yogurt bacteria improves lactose digestion in lactose maldigesters synergistically: A randomized, controlled, double-blind cross-over trial. Clin Nutr. (2015)
  9. Ojetti V, et al. The effect of oral supplementation with Lactobacillus reuteri or tilactase in lactose intolerant patients: randomized trial. Eur Rev Med Pharmacol Sci. (2010)
  10. Montalto M, et al. Effect of exogenous beta-galactosidase in patients with lactose malabsorption and intolerance: a crossover double-blind placebo-controlled study. Eur J Clin Nutr. (2005)
  11. Corazza GR, et al. beta-Galactosidase from Aspergillus niger in adult lactose malabsorption: a double-blind crossover study. Aliment Pharmacol Ther. (1992)
  12. Rosado JL, et al. Enzyme replacement therapy for primary adult lactase deficiency. Effective reduction of lactose malabsorption and milk intolerance by direct addition of beta-galactosidase to milk at mealtime. Gastroenterology. (1984)
  13. Cheng AH, et al. Long-term acceptance of low-lactose milk. Am J Clin Nutr. (1979)
  14. Solomons NW, Guerrero AM, Torun B. Dietary manipulation of postprandial colonic lactose fermentation: II. Addition of exogenous, microbial beta-galactosidases at mealtime. Am J Clin Nutr. (1985)
  15. Barillas C, Solomons NW. Effective reduction of lactose maldigestion in preschool children by direct addition of beta-galactosidases to milk at mealtime. Pediatrics. (1987)