Summary of Juniperus chinensis
Primary Information, Benefits, Effects, and Important Facts
Juniperus Chinensis is a plant that is a functional house decoration as it has some insect repellant properties. It has some folklore usage for some things, which has spurred limited amounts of research into the herb. Nothing substantial has been conducted though.
Currently, we have lackluster fat burning potential and one study in rats on blood glucose. This study on blood glucose is actually quite remarkable in effect size, but it needs to be replicated in another animal models since the active drug it was compared to might not have been properly evaluated chosen. The effects on colon cancer cells appear to be promising, but no studies have compared the potency of the active component (Widdrol) against an active drug control or used any living models to test; currently preliminary.
It does have a historical use of being an abortifacient (inducing abortions) so it is probably prudent to not consume Juniperus containing products if pregnant; no studies have been conducted on this, however.
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Things To Know & Note
Primary Function:
Also Known As
byakushin
Caution Notice
Examine.com Medical DisclaimerAnti-abortifacient means it can induce abortions via contractions of the uterine wall
Both the water-soluble and fat-soluble portions have benefits
How to Take Juniperus chinensis
Recommended dosage, active amounts, other details
The only animal evidence at this moment in time used 50-150mg/kg in rats, which is an estimated human dose of:
550-1,600mg for a 150lb person
700-2,200mg for a 200lb person
900-2,700mg for a 250lb person
There is no assurance that these dosage ranges are optimal for human consumption
Research Breakdown on Juniperus chinensis
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References
- ^ a b c d Widdrol from Juniperus chinensis induces apoptosis in human colon adenocarcinoma HT29 Cells.
- ^ Screening of Main Japanese Conifers for Antifungal Leaf Components, Sesquiterpenes of Juniperus chinensis var. pyramidalis.
- ^ Antimicrobial properties of heartwood, bark/sapwood and leaves of Juniperus species.
- ^ San Feliciano A, et al. Antineoplastic and antiviral activities of some cyclolignans. Planta Med. (1993)
- ^ Agrawal OP, Bharadwaj S, Mathur R. Antifertility effects of fruits of Juniperus communis. Planta Med. (1980)
- ^ Repellency of Milled Aromatic Eastern Red Cedar to Domiciliary Cockroaches (Dictyoptera: Blattellidae and Blattidae).
- ^ Carroll JF, et al. Essential oils of Cupressus funebris, Juniperus communis, and J. chinensis (Cupressaceae) as repellents against ticks (Acari: Ixodidae) and mosquitoes (Diptera: Culicidae) and as toxicants against mosquitoes. J Vector Ecol. (2011)
- ^ a b Chang CI, et al. A new phenolic and a new lignan from the roots of Juniperus chinensis. Nat Prod Commun. (2010)
- ^ a b c Lignans from leaves of Juniperus chinensis.
- ^ Studies on flavonoids in the leaves of Coniferae and allied plants. V. Relation between the distribution of bisflavonoids and taxonomic position of the plants.
- ^ Hinokiflavone.
- ^ Lim JP, et al. Free radical scavengers from the heartwood of Juniperus chinensis. Arch Pharm Res. (2002)
- ^ Three new diterpenes, 1,3-dioxototarol, isototarolenone, and 1-oxo-3β-hydroxytotarol, from the roots of Juniperus chinensis.
- ^ Lee CK, Cheng YS. Diterpenoids from the leaves of Juniperus chinensis var. kaizuka. J Nat Prod. (2001)
- ^ Serra S. Enantioselective synthesis of the bisabolane sesquiterpene (+)-1-hydroxy-1,3,5-bisabolatrien-10-one and revision of its absolute configuration. Nat Prod Commun. (2012)
- ^ Ali AM, et al. Antitumour-promoting and antitumour activities of the crude extract from the leaves of Juniperus chinensis. J Ethnopharmacol. (1996)
- ^ a b Extractives ofJuniperus chinensis L. I: Isolation of podophyllotoxin and yatein from the leaves ofJ. chinensis.
- ^ Chang CI, et al. A new labdane-type diterpene from the bark of Juniperus chinensis Linn. Nat Prod Res. (2008)
- ^ Essential oil composition of Juniperus chinensis from the plains of northern India.
- ^ Kim SJ, et al. Anti-obesity effects of Juniperus chinensis extract are associated with increased AMP-activated protein kinase expression and phosphorylation in the visceral adipose tissue of rats. Biol Pharm Bull. (2008)
- ^ a b c d Ju JB, et al. Comparison between ethanolic and aqueous extracts from Chinese juniper berries for hypoglycaemic and hypolipidemic effects in alloxan-induced diabetic rats. J Ethnopharmacol. (2008)
- ^ a b c Kwon HJ, et al. Widdrol induces cell cycle arrest, associated with MCM down-regulation, in human colon adenocarcinoma cells. Cancer Lett. (2010)
- ^ a b c d e Yun HJ, et al. Widdrol activates DNA damage checkpoint through the signaling Chk2-p53-Cdc25A-p21-MCM4 pathway in HT29 cells. Mol Cell Biochem. (2012)
- ^ Liang DT, Hodson JA, Forsburg SL. Reduced dosage of a single fission yeast MCM protein causes genetic instability and S phase delay. J Cell Sci. (1999)
- ^ Forsburg SL. Eukaryotic MCM proteins: beyond replication initiation. Microbiol Mol Biol Rev. (2004)