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Grape juice

Plain old grape juice isn't as popular as fermented grape juice (aka wine). However, grape juice does contain potentially beneficial phytochemicals. Grape juice has been tested in a small number of trials for outcomes including endurance exercise capacity, antioxidant potential, and memory.

Our evidence-based analysis on grape juice features 26 unique references to scientific papers.

Research analysis led by and reviewed by the Examine team.
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  1. ^ Vinson JA, Teufel K, Wu N. Red wine, dealcoholized red wine, and especially grape juice, inhibit atherosclerosis in a hamster model. Atherosclerosis. (2001)
  2. ^ De Oliveira E Silva ER, et al. Alcohol consumption raises HDL cholesterol levels by increasing the transport rate of apolipoproteins A-I and A-II. Circulation. (2000)
  3. ^ Meister KA, Whelan EM, Kava R. The health effects of moderate alcohol intake in humans: an epidemiologic review. Crit Rev Clin Lab Sci. (2000)
  4. ^ Burton R, Sheron N. No level of alcohol consumption improves health. Lancet. (2018)
  5. ^ Liska D, Kelley M, Mah E. 100% Fruit Juice and Dental Health: A Systematic Review of the Literature. Front Public Health. (2019)
  6. ^ Flood-Obbagy JE, Rolls BJ. The effect of fruit in different forms on energy intake and satiety at a meal. Appetite. (2009)
  7. ^ Blair CK, et al. Feasibility and preliminary efficacy of the effects of flavanoid-rich purple grape juice on the vascular health of childhood cancer survivors: a randomized, controlled crossover trial. Pediatr Blood Cancer. (2014)
  8. ^ Keevil JG, et al. Grape juice, but not orange juice or grapefruit juice, inhibits human platelet aggregation. J Nutr. (2000)
  9. ^ Yuan L, et al. Impact of apple and grape juice consumption on the antioxidant status in healthy subjects. Int J Food Sci Nutr. (2011)
  10. de Lima Tavares Toscano L, et al. A single dose of purple grape juice improves physical performance and antioxidant activity in runners: a randomized, crossover, double-blind, placebo study. Eur J Nutr. (2019)
  11. Toscano LT, et al. Potential ergogenic activity of grape juice in runners. Appl Physiol Nutr Metab. (2015)
  12. Neto MM, et al. Whole Red Grape Juice Reduces Blood Pressure at Rest and Increases Post-exercise Hypotension. J Am Coll Nutr. (2017)
  13. Siasos G, et al. Favorable effects of concord grape juice on endothelial function and arterial stiffness in healthy smokers. Am J Hypertens. (2014)
  14. Spettel S, et al. A prospective randomized double-blind trial of grape juice antioxidants in men with lower urinary tract symptoms. Neurourol Urodyn. (2013)
  15. Krikorian R, et al. Concord grape juice supplementation and neurocognitive function in human aging. J Agric Food Chem. (2012)
  16. Rowe CA, et al. Regular consumption of concord grape juice benefits human immunity. J Med Food. (2011)
  17. Dohadwala MM, et al. Effects of Concord grape juice on ambulatory blood pressure in prehypertension and stage 1 hypertension. Am J Clin Nutr. (2010)
  18. Hollis JH, et al. Effects of concord grape juice on appetite, diet, body weight, lipid profile, and antioxidant status of adults. J Am Coll Nutr. (2009)
  19. Park YK, et al. Changes in antioxidant status, blood pressure, and lymphocyte DNA damage from grape juice supplementation. Ann N Y Acad Sci. (2009)
  20. Park YK, Kim JS, Kang MH. Concord grape juice supplementation reduces blood pressure in Korean hypertensive men: double-blind, placebo controlled intervention trial. Biofactors. (2004)
  21. Albers AR, et al. The antiinflammatory effects of purple grape juice consumption in subjects with stable coronary artery disease. Arterioscler Thromb Vasc Biol. (2004)
  22. O'Byrne DJ, et al. Comparison of the antioxidant effects of Concord grape juice flavonoids alpha-tocopherol on markers of oxidative stress in healthy adults. Am J Clin Nutr. (2002)
  23. Chou EJ, et al. Effect of ingestion of purple grape juice on endothelial function in patients with coronary heart disease. Am J Cardiol. (2001)
  24. Haskell-Ramsay CF, et al. Cognitive and mood improvements following acute supplementation with purple grape juice in healthy young adults. Eur J Nutr. (2017)
  25. Krikorian R, et al. Concord grape juice supplementation improves memory function in older adults with mild cognitive impairment. Br J Nutr. (2010)
  26. Castilla P, et al. Concentrated red grape juice exerts antioxidant, hypolipidemic, and antiinflammatory effects in both hemodialysis patients and healthy subjects. Am J Clin Nutr. (2006)