Chaga
•Last Updated: July 21, 2023
Chaga, also known as Inonotus obliquus, is a mushroom commonly used as a dietary supplement. There are claims that it has beneficial effects on immune function and cancer prevention. However, these claims are limited to in vitro (studies done in petri dishes or test tubes) and animal studies, as there is only one study in humans.
Chaga is most often used for
Last Updated:July 21, 2023
1.^Konrad A Szychowski, Bartosz Skóra, Tadeusz Pomianek, Jan GmińskiInonotus obliquus - from folk medicine to clinical useJ Tradit Complement Med.(2020 Aug 22)
2.^Yangpeng Lu, Yanan Jia, Zihan Xue, Nannan Li, Junyu Liu, Haixia ChenRecent Developments in Inonotus obliquus (Chaga mushroom) Polysaccharides: Isolation, Structural Characteristics, Biological Activities and ApplicationPolymers (Basel).(2021 Apr 29)
3.^Myung-Ja Youn, Jin-Kyung Kim, Seong-Yeol Park, Yunha Kim, Channy Park, Eun Sook Kim, Kie-In Park, Hong Seob So, Raekil ParkPotential anticancer properties of the water extract of Inonotus corrected obliquus by induction of apoptosis in melanoma B16-F10 cellsJ Ethnopharmacol.(2009 Jan 21)
4.^Dong Pil Won, Jong Seok Lee, Duck Soo Kwon, Keun Eok Lee, Won Cheol Shin, Eock Kee HongImmunostimulating activity by polysaccharides isolated from fruiting body of Inonotus obliquusMol Cells.(2011 Feb)
5.^Jin Tian, Xiaoliang Hu, Dafei Liu, Hongxia Wu, Liandong QuIdentification of Inonotus obliquus polysaccharide with broad-spectrum antiviral activity against multi-feline virusesInt J Biol Macromol.(2017 Feb)
6.^Hong-Hui Pan, Xiong-Tao Yu, Ting Li, Hong-Ling Wu, Chun-Wei Jiao, Mian-Hua Cai, Xiang-Min Li, Yi-Zhen Xie, Yi Wang, Tao PengAqueous extract from a Chaga medicinal mushroom, Inonotus obliquus (higher Basidiomycetes), prevents herpes simplex virus entry through inhibition of viral-induced membrane fusionInt J Med Mushrooms.(2013)
7.^V A Shibnev, D V Mishin, T M Garaev, N P Finogenova, A G Botikov, P G DeryabinAntiviral activity of Inonotus obliquus fungus extract towards infection caused by hepatitis C virus in cell culturesBull Exp Biol Med.(2011 Sep)
8.^Haibo Mu, Amin Zhang, Wuxia Zhang, Guoting Cui, Shunchun Wang, Jinyou DuanAntioxidative properties of crude polysaccharides from Inonotus obliquusInt J Mol Sci.(2012)
9.^Xiangqun Xu, Yan Hu, Lili QuanProduction of bioactive polysaccharides by Inonotus obliquus under submerged fermentation supplemented with lignocellulosic biomass and their antioxidant activityBioprocess Biosyst Eng.(2014 Dec)
10.^Ye Chan Sim, Jong Seok Lee, Sarah Lee, Youn Kyoung Son, Jung-Eun Park, Jeong Eun Song, Suk-Jin Ha, Eock Kee HongEffects of polysaccharides isolated from Inonotus obliquus against hydrogen peroxide-induced oxidative damage in RINm5F pancreatic β-cellsMol Med Rep.(2016 Nov)
11.^Trishna Debnath, Sa Ra Park, Da Hye Kim, Jeong Eun Jo, Beong Ou LimAnti-oxidant and anti-inflammatory activities of Inonotus obliquus and germinated brown rice extractsMolecules.(2013 Aug 2)
12.^Chun-Jing Zhang, Jian-You Guo, Hao Cheng, Lin Li, Ying Liu, Yan Shi, Jing Xu, Hai-Tao YuSpatial structure and anti-fatigue of polysaccharide from Inonotus obliquusInt J Biol Macromol.(2020 May 15)
13.^Zhong Yue, Zhong Xiuhong, Yang Shuyan, Zheng ZhonghuaEffect of Inonotus Obliquus Polysaccharides on physical fatigue in miceJ Tradit Chin Med.(2015 Aug)
14.^Yang Hu, Chunying Teng, Sumei Yu, Xin Wang, Jinsong Liang, Xin Bai, Liying Dong, Tao Song, Min Yu, Juanjuan QuInonotus obliquus polysaccharide regulates gut microbiota of chronic pancreatitis in miceAMB Express.(2017 Dec)
15.^E A Dosychev, V N BystrovaTreatment o psoriasis using "Chaga" fungus preparationsVestn Dermatol Venerol.(1973 May)
16.^Jasmina Glamočlija, Ana Ćirić, Miloš Nikolić, Ângela Fernandes, Lillian Barros, Ricardo C Calhelha, Isabel C F R Ferreira, Marina Soković, Leo J L D van GriensvenChemical characterization and biological activity of Chaga (Inonotus obliquus), a medicinal "mushroom"J Ethnopharmacol.(2015 Mar 13)
17.^Sua Lee, Hwa Young Lee, Yohan Park, Eun Jeong Ko, Tae Hyun Ban, Byung Ha Chung, Hyun Soon Lee, Chul Woo YangDevelopment of End Stage Renal Disease after Long-Term Ingestion of Chaga Mushroom: Case Report and Review of LiteratureJ Korean Med Sci.(2020 May 18)
18.^Yuko Kikuchi, Koichi Seta, Yayoi Ogawa, Tatsuya Takayama, Masao Nagata, Takashi Taguchi, Kensei YahataChaga mushroom-induced oxalate nephropathyClin Nephrol.(2014 Jun)
20.^You-Min Ying, Lin-Yan Zhang, Xia Zhang, Hai-Bo Bai, Dong-E Liang, Lie-Feng Ma, Wei-Guang Shan, Zha-Jun ZhanTerpenoids with alpha-glucosidase inhibitory activity from the submerged culture of Inonotus obliquusPhytochemistry.(2014 Dec)
21.^John Knight, Kumudu Madduma-Liyanage, James A Mobley, Dean G Assimos, Ross P HolmesAscorbic acid intake and oxalate synthesisUrolithiasis.(2016 Aug)
22.^S Mashour, J F Turner Jr, R MerrellAcute renal failure, oxalosis, and vitamin C supplementation: a case report and review of the literatureChest.(2000 Aug)
23.^Jorge Lamarche, Reji Nair, Alfredo Peguero, Craig CourvilleVitamin C-induced oxalate nephropathyInt J Nephrol.(2011)
24.^Weijie Violet Lin, Christie Gloria Turin, David Walter McCormick, Christopher Haas, Gregory ConstantineAscorbic acid-induced oxalate nephropathy: a case report and discussion of pathologic mechanismsCEN Case Rep.(2019 Feb)