Calorie Blockers are compounds that block some amount of carbs and fats from being absorbed after they are eaten, and thus prevents these calories from acting in the body. They can reduce the caloric influence of excess, although may cause intestinal discomfort at higher doses.

This page features 3 unique references to scientific papers.

Research analysis by and verified by the Research Team. Last updated on Apr 29, 2017.


Calorie-blockers are compounds that prevent the intestinal uptake of either fatty acids or carbohydrates.

These typically work by either acting on the Pancreas (organ) to prevent the release of fat and carbohydrate digesting enzymes (such as lipase and amylase), or to physically bind to either the enzyme after release or the substrate itself and prevent the enzyme from exerting it's effects on said substrate.

Calorie-blockers are typically used to alleviate the caloric load of a cheat meal, although fat-blockers are sometimes used to prevent the uptake of fat-soluble toxins in foods where one aims to absorb a water soluble compound (as is the case with cinnamon).

Things to Know

Also Known As

Fat-Blocker, Carb-Blocker, Starch-Blocker, Fat-Blockers, Lipase Inhibitors, Amylase Inhibitors

Caution Notice

Fat-blockers should not be taken in situations where one can benefit from the fatty acid being absorbed, as is the case of fish oil supplementation.

Overusage of calorie-blockers may result in loose stool, as that stuff has to leave your body somehow and fatty acids (especially) make good colonic lubricant. Medical Disclaimer

Editors' Thoughts on Calorie-Blocker

Calorie-Blockers are never 100%.

Do not think that you can take some green tea and kidney bean extract before a meal, binge, and then continue to lose weight. If anything that will just make you fat and give you very loose stool.

They can make good finishing touches to a diet plan, but should never be the primary focus.

Kurtis Frank

Scientific Support & Reference Citations

Scientific support for each compound can be found vicariously through their respective pages.

Via HEM and FAQ:

  1. Naz S, et al. Epigallocatechin-3-gallate inhibits lactase but is alleviated by salivary proline-rich proteins. J Agric Food Chem. (2011)
  2. Raederstorff DG, et al. Effect of EGCG on lipid absorption and plasma lipid levels in rats. J Nutr Biochem. (2003)
  3. Zhong L, Furne JK, Levitt MD. An extract of black, green, and mulberry teas causes malabsorption of carbohydrate but not of triacylglycerol in healthy volunteers. Am J Clin Nutr. (2006)