Introducing Evidence-based Keto: Your no-hype guide to the ketogenic diet
We've spent the past year analyzing the research on the keto diet, and have just released Evidence-based Keto.
Clocking in at over 200 pages with 500+ references, it's the unbiased guide you need to the ketogenic diet.
Summary of Brassinosteroids
Primary Information, Benefits, Effects, and Important Facts
Brassinosteroids are a class of steroid compounds found in plants, used to regulate and induce plant growth. They share many similarities with human steroid hormones, but are generally at too low of a dose to exert effects in humans (on hormonal profiles) via food consumption.
They have been implicated in mouse models on skeletal muscle growth, and in some cell lines show promise at being anti-carcinogens (cancer protective).
How to Take Brassinosteroids
Recommended dosage, active amounts, other details
There is not enough information for a recommend dosage at this time.
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Everything you need to know about the keto diet
When we asked our users what they wanted us to cover, many of them mentioned the keto diet.
So we listened. We spent the year looking up the research on the ketogenic diet to help guide you in your journey.
With Evidence-based Keto, Examine.com gives you all the scientific research, but in understandable language with tons of informative infographics. No opinion, no bias, no conflict of interest.
If you’re interested in keto, this is a must-have unbiased source.
Scientific Research on Brassinosteroids
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Brassinosteroids are polyhydroxylated compounds related to the structure of 5a-cholestane, a chemical structure similar to many androgenic compounds. The chemical class of brassinosteroids share similar actions of mammalians steroids, but act in plants mostly via genetically mediated factors.
One of the main sources of brassinosteroids is in pollens in order to induce growth. They act in micromolar concentrations, which helps to explain a past yield of 10mg from 230kg pollen. Brassinosteroids can be synthesized in laboratory settings.
In does of 20-60mg/kg bodyweight, a brassinosteroid found in mustard (28-Homobrassinolide, or 28-HB) was able to stimulate protein synthesis and concomitantly inhibit breakdown of muscle while increasing strength. The mode of adminstration was oral consumption via Akt phosphorylation, and the results were somewhat confounded with increases in food intake, although the magnitude of which is not causative of the differences seen in lean mass. No binding to the Androgen Receptor (AR) was noted, and no changes in serum testosterone noted.
- Asami T, Nakano T, Fujioka S. Plant brassinosteroid hormones. Vitam Horm. (2005)
- Müssig C, Fischer S, Altmann T. Brassinosteroid-regulated gene expression. Plant Physiol. (2002)
- Mitchell JW, et al. Brassins--a new family of plant hormones from rape pollen. Nature. (1970)
- Brassinolide, a plant growth-promoting steroid isolated from Brassica napus pollen.
- New Route for the Synthesis of (22S,23S)-28-Homobrassinolide.
- Acebedo SL, et al. Synthesis and biological activity of ring-A difluorinated brassinosteroids. Steroids. (2011)
- Esposito D, et al. Anabolic effect of plant brassinosteroid. FASEB J. (2011)
- Malíková J, et al. Anticancer and antiproliferative activity of natural brassinosteroids. Phytochemistry. (2008)
- Steigerová J, et al. Brassinosteroids cause cell cycle arrest and apoptosis of human breast cancer cells. Chem Biol Interact. (2010)