Quick Navigation

Boerhaavia diffusa

Boerhaavia diffusa is an herb with anti-cancer and anti-inflammatory properties.

Our evidence-based analysis on boerhaavia diffusa features 50 unique references to scientific papers.

Research analysis led by .
Reviewed by
Examine.com Team
Last Updated:

Summary of Boerhaavia diffusa

Primary information, health benefits, side effects, usage, and other important details

Boerhaavia diffusa is an herb found in Ayurveda and other traditional medicines. Historically, Boerhaavia diffusa has been used for its anti-diabetic and diuretic properties. In different areas of the world, Boerhaavia diffusa has also been used for pain relief, anti-inflammation, and treating indigestion. Boerhaavia diffusa is a tropical crawling root plant, with bioactive compounds in both the leaves and roots.

There have not been any human studies conducted on Boerhaavia diffusa, but animal evidence suggests it is an effective diuretic, and can suppress the proliferation of immune cells. This can be harmful in some cases, like during flu season, but beneficial if the immune system is hyperactive. Boerhaavia diffusa also has an anti-proliferative effect on some cancer cells, which means it prevents them from spreading. This anti-cancer effect comes from the isolated bioactive purnavarine.

Boerhaavia diffusa also has anti-oxidant properties.

Boerhaavia diffusa’s anti-inflammatory and anti-oxidative mechanisms are plausible explanations for _Boerhaavia diffusa’s potent anti-diabetic effects, which rivals the potency of standard drugs like Glibenclamide and Metformin. Further research is needed to confirm this relationship.

Get trusted answers to health questions that matter to you

Getting an Examine.com subscription makes it easy for you to stay informed and understand the latest nutrition research.

If you’re overwhelmed by all the possibilities of supplementation and want step-by-step instructions on what supplements to take (how much, when, and in what combinations), then the Examine.com Supplement Guides are perfect for you.

Your support keeps us 100% independent, so that we never have a conflict of interest.


How to Take

Medical Disclaimer

Recommended dosage, active amounts, other details

The standard Boerhaavia diffusa dose used in rat studies is in the range of 200-400mg/kg, with a maximally effective dose of 1000mg/kg. This translates to a human dosage of 32-64mg/kg, or:

• 2,200-4,300mg for a 150lb person

• 2,900-5,800mg for a 200lb person

• 3,600-7,200mg for a 250lb person

These are estimated doses based off of animal research. There have not been any human studies conducted on Boerhaavia diffusa.

Things to Note

Is a Form Of

Primary Function:

Also Known As

Punarnava

Caution Notice

Boerhaavia Diffusa appears to be immunosuppressive, and usage of this herb during periods of acute sickness (cold, flu, etc.) may not be advisable.

  • Some bioactives in the leaf (anti-inflammatory, immunosuppressive) are found in hot water extracts, suggesting a tea made from the leaves may have bioactivity

Get our free 5-day course on the essentials of supplementation.

At Examine.com, our incentives line up with yours — getting unbiased information. That's why we don’t sell any advertising or supplements.

Join over 250,000 people who have learned about effective versus overrated supplements, tips for buying supplements, and how to combine supplements for safety and efficacy.

Click here to see all 50 references.