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Discover The Best Combinations Of Supplements, Distilled Into 17 Easy-To-Follow-Guides

  • Know which supplements work for specific goals.
  • Reach peak efficiency by combining supplements.
  • Save $100s by skipping supplements that don't work.

What To Take For A Healthy Body

  • Heart & Circulation
  • Liver
  • Bones
  • Joints
  • Skin & Hair
  • Allergies & Immunity
  • Gastrointestinal Coming Soon

What To Take For AHealthy Lifestyle

  • Muscle Gain & Fitness
  • Testosterone Enhancement
  • Insulin Sensitivity & Glucose Uptake
  • Vegetarianism / Veganism
  • Fat Loss
  • Seniors

What To Take For AHealthy Mind

  • Memory & Focus
  • Anxiety New
  • Sleep Quality
  • Sex & Libido
  • Mood & Depression

In The Heart & Cardiovascular Supplement Guide, You'll Discover

  • Cocoa
  • CoQ10
  • Taurine
  • Pine Bark
  • Stimulants

In The Heart & Cardiovascular Supplement Guide, You'll DiscoverHow To Take & Combine These Supplements

  • + +
    For general cardiovascular health

    There are 3 core supplements everyone can benefit from. Learn the right doses and time of day to take them.

  • +
    For athletes seeking top performance

    Learn what to take 1h before breakfast and 1-2h before exercise.

  • + + +
    For preventative care

    See recommended supplements and dietary advice for preventative care. We even provide alternatives for vegans, for people with hypertension, and for those with raised triglycerides.

  • + + +
    For people who suffered a heart attack

    See what to take with your meal.

  • +
    For people with vericose veins

    If the core supplements and these options don't work within 1 month, we provide 4 more options.

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In The Liver Supplement Guide, You'll Discover

  • Choline
  • TUDCA
  • Spirulina

In The Liver Supplement Guide, You'll Discover How To Take & Combine These Supplements

  • +
    For general liver health

    There are 2 core supplements everyone can benefit from. Learn the right doses and time of day to take them. One of these needs can be met with your diet instead.

  • +
    For people with fatty liver

    Know what to take and how much.

  • +
    For people with cholesterol-rich gallstones in the liver

    Know what supplements to take with your meals to alleviate this specific type of gallstone.

  • + +
    For after a night of drinking

    Know what to take the morning after and 4-6 hours later.

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In The Bones Supplement Guide, You'll Discover

  • Vitamin D
  • Coral calcium
  • Vitamin D + Calcium

In The Bones Supplement Guide, You'll Discover How To Take & Combine These Supplements

  • + +
    For general bone health

    There are 2 core supplements everyone can benefit from. Learn the right doses and time of day to take them.

  • +
    For people low on 2 key minerals

    There are 2 more minerals key to bone health, however you may get enough through your diet. See our dietary recommendations.

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In The Joints Supplement Guide, You'll Discover

  • Boswellia Serrata
  • Curcumin
  • MSM

In The Joints Supplement Guide, You'll Discover How To Take & Combine These Supplements

  • + + +
    For osteoarthritis

    There 4 key supplements that work together. Learn which 2 additional supplements to add after 1 month. Also learn how to increase absorption by adding another supplement to your stack.

  • + + +
    For rheumatoid arthritis

    Learn which 3 supplements you should be taking.

  • + + +
    For complex regional pain syndrome

    One important vitamin can reduce the risk of CRPS. Learn what to take and how much.

  • + + +
    For general joint pain

    You can take supplements from the "rheumatoid arthritis" or "osteoarthritis" stacks. We'll also give you some additional options.

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In The Skin & Hair Supplement Guide, You'll Discover

  • Vitamin A
  • Creatine
  • Vitamin E
  • Creams with Vitamin E

In The Skin & Hair Supplement Guide, You'll Discover How To Take & Combine These Supplements

  • +
    For sun protection

    There is one supplement you can take once a day. Learn how it works.

  • +
    For thicker, smoother, tighter skin

    There are two types of creams that work.

  • +
    For acne

    Take a specific type of mineral, alongside a healthy diet, excercise plan, and good hygiene.

  • +
    For reducing skin redness

    A cream containing these two vitamins, applied nightly, can help.

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In The Allergies & Immunity Supplement Guide, You'll Discover

  • Garlic
  • Echinacea

In The Allergies & Immunity Supplement Guide, You'll Discover How To Take & Combine These Supplements

  • +
    For general health

    There are 2 core supplements everyone can benefit from, especially in flu season. Learn the right doses and time of day to take them.

  • +
    For first signs of respiratory infection

    There is something you can take along with the core supplements that should help.

  • +
    For onset of illness

    A common mineral can help.

  • +
    For chronic stuffy nose

    If the core supplements don't work, there are 2 more options for you.

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In The Muscle Gain & Fitness Supplement Guide, You'll Discover

  • Protein
  • Creatine
  • Nitrates
  • HMB
  • Glutamine

In The Muscle Gain & Fitness Supplement Guide, You'll Discover How To Take & Combine These Supplements

  • + +
    For general muscle gain and fitness

    There are 3 core supplements everyone can benefit from. Learn the right doses and time of day to take them.

  • + + +
    For weight lifters

    See what you should take a half hour before strenuous exercise.

  • + +
    For alertness and endurance during long sessions

    You can take one supplement with a meal and another before exercise.

  • + + +
    For intense training like HIIT

    Learn which 2 supplements to take with a meal an hour before training. We'll also tell you the ratio of protein-to-carbs to take after exercise.

  • + +
    For exercise after missing meals

    We'll tell you what to eat and how to supplement to get back on track.

  • +
    For mental fatigue

    There is a class of supplements that can help with mental fatigue during and after a workout without hindering the other supplements.

  • +
    For more nitrate with less bulk

    If you find it impractical to eat lots of nitrate-rich vegetables, there is something more concentrated you can substitute.

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In The Testosterone Enhancement Supplement Guide, You'll Discover

  • DHEA
  • Boron
  • Libido Enhancers

In The Testosterone Enhancement Supplement Guide, You'll Discover How To Take & Combine These Supplements

  • + +
    For general testosterone boosting

    There are 3 core supplements everyone can benefit from. Learn the right doses and time of day to take them.

  • + +
    For boosting in young men

    Supplements should be taken with a meal containing fat. There are two additional supplements young men can add.

  • +
    For support in middle-aged men

    The core supplements should be taken with a meal containing fat. There is another supplement that can be added that may help.

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In The Insulin Sensitivity & Glucose Uptake Supplement Guide, You'll Discover

  • Zinc
  • Corosolic Acid

In The Insulin Sensitivity & Glucose Uptake Supplement Guide, You'll Discover How To Take & Combine These Supplements

  • + +
    For diagnosed insulin resistance

    There are 3 supplements to take with meals. An additional supplement is recommended for people who eat a lot of carbs.

  • + +
    For undiagnosed insulin resistance

    A combination of 3 supplements will work in tandem with dietary changes and exercise.

  • + +
    For increasing glucose uptake during workouts

    There is a key supplement to take once a day and another to take before workouts.

  • + +
    For increasing glucose uptake during meals

    There is one key supplement to take once a day. There are additional supplements to boost its effectiveness.

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In The Vegetarianism/Veganism Supplement Guide, You'll Discover

  • Vitamin B12
  • Iron + Vitamin C

In The Vegetarianism/Veganism Supplement Guide, You'll Discover How To Take & Combine These Supplements

  • +
    For general benefits

    There are 4 core supplements all vegans/vegetarians can benefit from. Learn the right doses and time of day to take them.

  • + +
    For athletes

    There is an additional supplement you can take. There is also one that might help improve focus when taken 30-45 min before exercise.

  • +
    For more protein

    See our recommendations for protein supplementation.

  • +
    For people avoiding salt

    When avoiding salty foods, you can miss out on one important element. There is a simple supplement you can take to compensate, unless you're getting it through certain foods.

  • +
    For people who don't get enough sun

    Take a certain vitamin with a meal containing fat.

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In The Fat Loss Supplement Guide, You'll Discover

  • Protein
  • Caffeine
  • Fiber
  • Berberine
  • Raspberry Ketone

In The Fat Loss Supplement Guide, You'll Discover How To Take & Combine These Supplements

  • For general fat loss

    Protein is the main supplement you should be taking. Learn the right doses and time of day to take it.

  • + + +
    For burning fat with stimulants

    You start by taking caffeine. Once tolerance sets in, there are two more supplements to add. Ovr the next 12 weeks, you can increase the effect with 2 more supplements. There is a supplement you can take with the caffeine that helps avoid overstimulation while retaining the benefits to attention and focus. There are other stimulants you can take instead of caffeine.

  • + + +
    For burning fat without stimulants

    You can avoid caffeine and other stimulants. Instead, you increase your fiber intake (we'll tell you how) and add 3 different supplements.

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In The Supplement Guide For Seniors

  • Vitamin B12
  • Protein
  • Vitamin E
  • Folic Acid

In The Supplement Guide For SeniorsHow To Take & Combine These Supplements

  • + + +
    For general health

    There are 3 core supplements all seniors can benefit from. Learn the right doses and time of day to take them.

  • +
    For increased energy and stamina

    There are 2 supplements you can add to the core supplements. A third one is optional.

  • +
    For improved cognition

    There is a supplement you can take once in the morning and once in the afternoon. Another is taken once with a meal.

  • +
    For improved immunity

    There is a vitamin that may help.

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In The Memory & Focus Supplement Guide, You'll Discover

  • Vitamin B12
  • Vitamin E
  • Fish Oil
  • Calcium

In The Memory & Focus Supplement Guide, You'll Discover How To Take & Combine These Supplements

  • For general memory and focus

    There is 1 core supplement everyone can benefit from, and you'll be surprised by what it is. It's supported by a large body of evidence. Learn the right doses and time of day to take it.

  • +
    For improved long-term memory formation

    There is another good supplement you'll want to take and then you can choose 1 of 3 additional supplements.

  • +
    For improved attention span

    Add caffeine to your stack along with 1 other supplement. We'll provide info on building up your tolerance and how to reset if your caffeine intake is already high.

  • +
    For for those cutting down on meat

    There is 1 supplement that could be beneficial for you.

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In The Anxiety Supplement Guide, You'll Discover

  • Kava
  • Ashwagandha
  • Alcohol
  • Yohimbine

In The Anxiety Supplement Guide, You'll Discover How To Take & Combine These Supplements

  • For general anxiety relief

    There is 1 core mineral everyone can benefit from that's easy to get enough in a regular diet. Learn which foods contain this mineral. If you need a supplement, learn the right doses and time of day to take them.

  • + +
    For generalized anxiety disorder (GAD)

    We recommend to supplement with the core supplement to eliminate the possibility of deficiency as the cause. After a week, you can add 1 or 2 helpful supplements. We'll tell you which.

  • +
    For anxiety due to accumulated stress

    You can choose one of several supplements. Some can be taken in the evenings and will not cause insomnia. Other should only be taken during the day.

  • + +
    For state and trait anxiety

    You should see results after a week when taking these two proven supplements.

  • + +
    For panic attacks

    There is 1 proven supplement you can add. There is another that may work, but has no human evidence supporting it yet.

  • +
    For anxiety related to PMS

    There is a supplement that can help, and you have several versions to choose from.

  • +
    For improved sleep

    If poor sleep is contributing to your anxiety, we recommend 1 of 2 supplements to be taken before bed.

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In The Sleep Quality Supplement Guide, You'll Discover

  • Magnesium
  • Lemon Balm
  • Caffeine

In The Sleep Quality Supplement Guide, You'll Discover How To Take & Combine These Supplements

  • For general sleep quality

    There is 1 core supplement everyone can benefit from. Learn the right doses and time of day to take them.

  • + +
    For anxiety and intrusive thoughts

    There are two supplements you can add to your stack that should help.

  • + +
    For feeling rested in the morning

    You can take one or both of these proven supplements, 30-60 min before bed.

  • +
    For falling asleep faster and jet lag

    If the core supplement doesn't help you within 2 weeks, there is one popular supplement that should work.

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In The Sex & Libido Supplement Guide, You'll Discover

  • Maca
  • Fenugreek
  • Proprietary blends

In The Sex & Libido Supplement Guide, You'll Discover How To Take & Combine These Supplements

  • +
    For general libido enhancers

    There are 2 core supplements everyone can benefit from. Learn the right doses and time of day to take them. Make sure you consume enough calories and fat to maintain your libido over time.

  • +
    For men and women to increase libido

    If the core supplement doesn't work within a month, there are 3 more you can try. You shouldn't combine them - instead rotate them every month.

  • +
    For erectile rigidity

    There is a supplement you can take 30 min before sexual activity that should help.

  • +
    For erectile dysfunction due to poor blood flow

    There is another supplement you can add to your stack. If that doesn't work, there are several more supplements to try.

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In The Mood & Depression Supplement Guide, You'll Discover

  • St. John's Wort
  • Zinc
  • NAC

In The Mood & Depression Supplement Guide, You'll Discover How To Take & Combine These Supplements

  • +
    For general mood

    There are 3 core supplements can help regulate your mood. Learn the right doses and time of day to take them.

  • +
    For people with a major depressive disorder or those taking medication

    You should consult with a doctor about adding this supplement to your core supplements.

  • +
    For people feeling depressed and not on medication

    There is a common herb that should help.

  • +
    For improved mood and reduced stress

    There is a type of supplement you can add. You can choose one of two types. One of these should not be taken in the evenings.

  • +
    For improved mood and reduced agitation and irritability

    Add this supplement to your stack. Unlike other mood boosters, this one works the opposite way. Read more in the guide about how it works.

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OR

Save $700 When You Buy All 17 Guides And You'll Also Get All Future Guides

Download All 17 Guides For Only $149 $249.99
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Includes All Current And Future Guides

  • Heart & Circulation
  • Liver
  • Bones
  • Joints
  • Skin & Hair
  • Allergies & Immunity
  • Gastrointestinal Coming Soon
  • Muscle Gain & Fitness
  • Testosterone Enhancement
  • Insulin Sensitivity
  • Vegetarianism / Veganism
  • Fat Loss
  • Seniors
  • Memory & Focus
  • Anxiety New
  • Sleep Quality
  • Sex & Libido
  • Mood & Depression

Sample Page From Our Easy-To-Follow Guides

Each supplement and the evidence for it is covered in Plain English.

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AS MENTIONED IN

  • The Guardian
  • Men's Health
  • Men's Fitness
  • Livestrong
  • The Huffington Post
  • Muscle and Fitness
  • Costco Connection
  • BodyBuilding.com
  • AskMen.com
  • Business Insider
  • Boston Globe
  • Daily Burn
  • Fast Company
  • Greatist
  • Lifehacker
  • Medpage Today
  • Yahoo Sports
  • About
  • MSN

Respected By Industry Experts

Eric Cressey loves our unbiased perspective

MA in Kinesiology, Certified Strength and Conditioning Specialist

Bio: Eric is the president and co-founder of Cressey Sports Performance. Eric is perhaps best known for his extensive work with baseball players, with more than 100 professional players traveling to train with him each off-season. As a competitive powerlifter, Eric holds several state, national, and world records. He is the author of many books.

The supplement industry can be tremendously confusing for a number of reasons. First, the margins are incredibly high - so there are a lot of unethical weasels with no scientific background making bold and unsubstantiated claims to separate you from your money. Second, it's a dynamic industry, as new products, brands, and research emerge every single day. Fortunately, the guys at Examine.com have streamlined the process of educating us all by providing an incredibly up-to-date resource on the supplements we encounter on a daily basis, as well as some of the more obscure ones that are out there that might 'stump' us. This is an excellent product not only because it's a completely research-backed, unbiased perspective without any financial conflicts of interest, but also because it's exhaustively thorough and well written. I highly recommend it.

Dr Joanna McMillan prefers seeing the evidence

PhD

BIO: Joanna is the founder of Get Lean and a regular on Australian television and radio. She is a trained fitness instructor. She has authored 6 books and has a weekly column on fitness and nutrition.

As a science-trained nutritionist, my entire work must be evidence-based if we are not to be constantly swayed by hyped up marketing claims or people's theories. But keeping abreast of research in every area of nutrition is impossible. When this guide landed in my inbox I was stoked. It is now an invaluable resource for my work. I have at my fingertips the studies to date on a particular supplement, I can click through to read them and I can see in one glance the conclusions that can be drawn. For anyone using or advising on supplement use, I cannot recommend this guide highly enough.

Dr Bryan Chung found something not found in any other resource

MSc in Rehabilitation Science, MD, PhD

BIO: Dr. Chung is a practicing plastic surgeon and a clinical researcher. His interests include clinical trials design, the development of outcome tools in clinical research, and systematic reviews of existing evidence in medicine, with a particular interest in surgical research as well as fitness/nutrition topics. He sits on the editorial board of the Clinical Journal of Sport Medicine.

Examine.com has become THE repository resource for nutritional supplement information. Most other similar databases fail at what they're good at, which is being accessible and being comprehensive. Their frequent updates stay on top of the literature as it evolves. Examine.com gives me an excellent overview of the body of work, which helps me filter and refine my search strategy when I'm looking up supplements that I get asked about that I've never heard of. The Human Effect Matrix provides interpretation that is lacking in every other supplement database in the world. Most people don't have the time or interest to develop high-level expertise, but need somewhere to turn to to make informed decisions about their supplements. That information is at Examine.com.

Dr. Jose Antonio knows it's the real deal

PhD. Co-founder, International Society Of Sports Nutrition (ISSN)

BIO: Dr. Antonio is an Assistant Professor of Exercise and Sports Science at Nova Southeastern University. He's written over a dozen book and is a regular lecturer all over the country.

Examine.com rocks! It's a great source of information on the science of dietary supplements. Plenty of real science, no bro-science. It's the real deal. Kudos to Sol Orwell and Kurtis Frank for showing the rest of the nutrition world that indeed, there's plenty of science in the field of dietary supplements. Pass me the creatine please! :-)

Dr. Yoni Freedhoff says rely on research over opinion

MD CCFP Dip ABBM

BIO: Dr. Freedhoff is Assistant Professor of Family Medicine at the University of Ottawa. Canadian Medical Association Journal once dubbed him a Canadian "nutritional watchdog". His advocacy efforts in both obesity and nutrition policy have landed him speaking at both the Canadian House of Commons and Canada's Senate regarding his concerns surrounding Canada's Food Guide and as a member of multiple stakeholder groups run by the Public Health Agency of Canada and Health Canada. Dr. Freedhoff is quoted regularly in the national and international press, appears frequently on television.

It's insufficient to simply rely on belief, conjecture or internet advice to determine if supplements are right for you. Instead you need to rely on research. With Examine.com's reference guide not only will you find their summary of the research, but also links to the original papers should you want to do your own due diligence. Truly a massive and helpful undertaking.

Emma-Leigh Synnott knows where to find answers

MBBS, BVsc

BIO: Emma graduated in medicine from Sydney University, and is currently undertaking specialist physician training in Rehabilitation Medicine. She is a certified Sports Nutrition Specialist with the International Society of Sports Nutrition, and is an accredited Australian Strength and Conditioning Association Level 1 Strength and Conditioning Coach.

During my years of study in science and Medicine one of the first and most powerful messages elucidated is that you will never have all the answers. So as a consequence you rapidly discover how to go about finding those answers... Years later I can honestly say that my go to evidence-based information source on supplements would have to be Examine.com. Unbiased and meticulously put together, Examine.com provides a clear and detailed resource for novices and professionals alike.

Frequently Asked Questions

How Are Examine.com Guides Different?

Most supplement research comes with an inherent bias. Studies are often backed by supplement companies with a vested interest to arrive at a conclusion substantiating their claims. All of this is done with one purpose in mind - to make you spend your money on pills and powders which may not work.

Other companies that don't do research themselves just cherrypick studies that make their products look good. Often time these are studies performed on rats and in Petri dishes

As Examine.com is an independent company that does not sell any supplements, we do not cherrypick. We are not trying to sell you supplements. We are 100% neutral and conduct all of our research independently, allowing us to come to our own conclusions regarding the validity of which supplements work.

Are Examine.com Guides useful to regular folks like me, who are not researchers or athletes?

Absolutely. The Supplement Guides are actually written with our own mothers in mind. They are easy-to-read and give you simple step-by-step directions on which supplements to take (and which to not waste money on).

How are the Supplement Guides different from A-to-Z Supplement Reference?
  • Supplement Guides are easy-to-follow with step-by-step instructions. They can be easily used by your mother or father! A-to-Z Supplement Reference contains the raw data in over 1000 pages. Not very friendly for the layperson.

Unless you are a researcher, you should choose a Supplement Guide.

All Guides Are Written By Unbiased Researchers

We look for new scientific research and summarize the findings for you in Plain English.

Kamal Patel

Director

Kamal is a nutrition researcher with an MPH and MBA from Johns Hopkins University, and is on hiatus from a PhD in nutrition in which he researched the link between diet and chronic pain. He has published peer-reviewed articles on vitamin D and calcium as well as a variety of clinical research topics. Kamal has also been involved in research on fructose and liver health, mindfulness meditation, and nutrition in low income areas.

Gregory Lopez

MA in Molecular Biophysics, PharmD

Gregory enjoys bringing his quantitative and analytical skills to bear on issues relevant to people's health and well-being.

Bill Willis

PhD in Biomedical Science

An avid member of the fitness industry for the past 15 years, Bill is currently a postdoctoral fellow, where he is examining the role of metabolic stress in the control of protein synthesis and inflammation in health and disease.

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Zero Conflict of Interest

Examine.com is an unbiased nutrition and supplement resource. We are not influenced by commercial interests, product manufacturers, or any other organization, and we will not advertise products or brands. Examine.com does not accept donations, third-party funding, or sponsorship of any kind. One hundred percent of our revenue is generated through our three products: the Examine.com Research Digest, A-to-Z Supplement Reference, and the Supplement Guides.