IMPORTANT NOTICE: The stack pages are not being updated and have been kept for archival purposes.
Due to the extreme complexity of stacking with proper consideration to demographics such as age, requirements, and gender, we have released a far more encompassing fit - The Supplement Guides
With FREE lifetime updates and authored by over a dozen researchers, it is the clearest guide to supplementation there is.
Polycystic Ovarian Syndrome Overview:
A collection of supplements that are either proven or thought to significantly improve symptoms of PCOS in women.
2,000mg (2g) of myo-inositol twice daily (4,000mg total, although a single dose seems to be fine as well) appears to be effective over the course of a few months to reduce the abnormalities in glucose and androgen metabolism seen in PCOS. Improved fertility has been noted, and while weight loss in PCOS is somewhat unreliable with supplemental inositol it has been noted in women of all body weights.
The recommended dose is actually at the higher range of acceptable doses (2,000-4,000mg seems best) and it is possible to pair myo-inositol with D-chiro-inositol in a 40:1 ratio (many studies using 550mg and 13.8mg respectively) which appears to be equally effective but faster acting and needing a lower overall dose.
The reference drug for PCOS currently is Metformin due to its AMPK activating abilities and improvements to glucose metabolism and insulin sensitivity. Berberine is a replacement for Metformin when it is not available and are considered interchangeable for the most part (if already using Metformin, stick with Metformin).
The aforementioned dose is to be split in up to four divided doses and taken alongside meals. It would be advisable to start at the lower end of the scale (300mg thrice daily) and work up to the maximum dosage (500mg four times daily) if the lower does is not working after a few months.