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Supplements that have been suggested or otherwise shown to control symptoms associated with menopause. Due to the low amount of highly effective compounds for Menopause, this page currently contains both effective compounds as well as those that are likely to have benefit but require further research; the page will be pruned in the future.
2.5-10mg refers to an isopropanolic extract, which is usually sold under the brand name Remifemin. Reliability with this extract seems higher than with general Black Cohosh root powder, but there is some industry influence in the results. Basic root powder (dry weight, ethanolic extract) should be taken in doses between 36-128mg daily, usually with meals.
Black Cohosh is non-estrogenic, but it may not be the best supplement to take as many studies conducted on it noted that the magnitude of benefit was very small and possibly not significantly different than placebo.
DHEA may reduce the side-effects associated with menopause, such as hot flashes and night sweats. However, the high potency that tends to be attributed to DHEA is met with low reliability in the results. The effects may be more prominent in persons suffering from chronic stress or with elevated cortisol levels. DHEA is estrogenic.
1-3g of Royal Jelly daily appears to exert estrogenic effects and alleviates some side-effects associated with menopause that are due to estrogen deficiency, thus Royal Jelly contains phytoestrogens.
The efficacy of Royal Jelly in humans right now is confounded; a few studies have been conducted with promise, but they have been testing nutrient combinations of which RJ is just one factor.
The above dosage refers to a basic berry extract, if using a patented extract Ze110 requires 20mg and BNO1095 required 4mg. Taken once in the morning with food.
Vitex Agnus Castus (VAC) is currently the most well supported herbal intervention for menopausal symptoms and PMS, and is non-estrogenic.
20-50mg of Pueraria Mirifica is likely to attenuate side-effects associated with menopause due to the phytoestrogens it contains.
Trials on Pueraria Mirifica are promising, but at the same time they are subpar quality and many do not have proper blinding protocols on them; the promise and efficacy they show may be less when considering the placebo effect.
This herb is highly estrogenic, more-so than any other herb in this list.