Fatigue and Stress (Chronic)

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If you want to know what supplements to take for Fatigue and Stress (Chronic)...

Sleep Quality Supplement Guide

Fatigue and Stress (Chronic) Overview:

This list is for supplements that show promise in preventing or reversing what is known as 'metabolic burnout' or simply 'burnout', which is excessive workload and low-grade stressors over a long period of time accumulating and then causing an exhausted state similar to fatigue and stress. Some other complications, such as anxiety or depression, may manifest secondary to this state.

Suggested Supplements

Rhodiola Rosea

Dosage: 288-680mg

The 288-680mg range is what is used in human studies, and assumes an extract that is standardized for 3% rosavins and 1% salidroside. The higher dose is recommend for one time usage, and the lower dose is recommended for daily usage.

Rhodiola rosea is one of the most well researched adaptogen compounds, and appears to be particularly effective against prolonged stress and fatigue. It has been implicated in both preventative and rehabilitative uses, and has a (relatively) large body of human evidence to support its effects.


Dosage: 2-6g

2-6g L-ornithine is the standard recommended dosage. This dosage has shown anti-fatigue effects in scenarios where there is an excessive level of ammonia in the blood; ammonia is inherently pro-fatigue, and it is known to be spiked in some liver disorders (hepatic encepalopathy) or prolonged exercise and it is suspected that long work hours may predispose persons to higher than average circulating ammonia concentrations.

L-Ornithine is unlikely to have any benefit in persons who do not have elevated ammonia concentrations.

If you want to know what supplements to take for Fatigue and Stress (Chronic)...

Sleep Quality Supplement Guide