Studies related to PMS and Vitamin B₆

Effect Of Combined Use Of Calcium And Vitamin B6 On Premenstrual Syndrome Symptoms: A Randomized Clinical Trial

Effect Decrease
Values Mean + SD. Physical symptoms: Vitamin B6: before 0.53 (0.33), after 0.42 (0.46). Combination: before 0.57 (0.31), after 0.25 (0.15). Psychological symptoms: Vitamin B6: before 0.61 (0.36), after 0.47 (0.37). Combination: before 0.74 (0.37), after 0.26 (0.21). General Symptoms: Vitamin B6: before 0.61 (0.35), after 0.44 (0.32). Combination: before 0.72 (0.33), after 0.25 (0.17).
Trial Design Non-controlled trial
Trial Length 1-6 months
Number of Subjects 76
Sex Female
Notes for this study:
In a randomized, double-blind, controlled trial, 76 women with premenstrual syndrome were allocated to take either 40 mg of vitamin B6 daily or 40 mg of vitamin B6 daily with 500 mg of calcium for 2 months.
Score on Daily symptom records for physical, mental and general symptoms improved notably more for the combination group than for the group that only received vitamin B6, all differences being statistically significant. Compared with baseline, the vitamin B6 group saw a small but statistically significant reduction in psychological symptoms and general symptoms, and a nonsignificant reduction in physical symptoms.

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