| Effect | None |
| Trial Design | Double blind |
| Trial Length | 2-4 Weeks |
| Number of Subjects | 19 |
| Gender | Both Genders |
| Age Range | 45-64 |
| Body Types | Obese, Overweight |
In type 2 diabetics given high dose alpha-tocopherol supplements (1,200 IU) daily for four weeks, while baseline DNA damage did not appear to be altered the increase in oxidation expected after an oral glucose tolerance test was exacerbated resulting in 13.6% more DNA damage relative to placebo.
| Effect | Increase |
| Trial Design | Double blind |
| Trial Length | 2-4 Weeks |
| Number of Subjects | 19 |
| Gender | Both Genders |
| Age Range | 45-64 |
| Body Types | Obese, Overweight |
In type 2 diabetics given high dose alpha-tocopherol supplements (1,200 IU) daily for four weeks, while baseline DNA damage did not appear to be altered the increase in oxidation expected after an oral glucose tolerance test was exacerbated resulting in 13.6% more DNA damage relative to placebo.
| Effect | None |
| Trial Design | Double blind |
| Trial Length | 1-6 months |
| Number of Subjects | 40 |
| Gender | Both Genders |
| Age Range | 45-64 |
| Body Types | Obese |
Supplementation of 400IU alpha-tocopherol daily for eight weeks in type II diabetics noted that, despite diabetics having higher baseline DNA oxidative damage relative to nondiabetics, that supplemental vitamin E failed to modify this as well as LDL oxidation.