Effects Of Gamma-tocopherol Supplementation On Thrombotic Risk Factors
Effect | Decrease |
Trial Design | Double blind |
Trial Length | 1-6 months |
Number of Subjects | 39 |
Sex | Both Genders |
Age Range | 18-29, 30-44 |
Body Types | Average |
Supplementation of gamma-tocopherol at 100mg or 200mg daily over a period of five weeks in otherwise healthy subjects noted a small reduction in platelet aggregation at the lower dose only, with other paramters not significantly affected (a mild reduction in LDL and increase in HDL was present at the lower yet not higher dose, despite dose-dependent increases in plasma gamma-tocopherol).
P-selectin (a cell adhesion factor) was decreased in both supplemental groups () with no apparent dose-dependent effects.