Effect | Decrease |
Trial Design | Non-controlled trial |
Trial Length | 6+ Months |
Number of Subjects | 22 |
Sex | Both Genders |
Age Range | 30-44 |
Body Types | Overweight |
Supplementation of alpha-tocopherol (300mg) daily for one year in persons with NAFLD after a six month introductory period (lifestyle and diet modification) noted that the addition of vitamin E was able to reduce circulating ALT in persons with NAFLD but not steatohepatitis although fibrotic, inflammation, and steatitis scores of those with steatohepatitis were improved with vitamin E; both groups experienced a reduction in circulating TGF-b.