Studies related to Vaccine Augmentation and Vitamin E

Vitamin E Supplementation And In Vivo Immune Response In Healthy Elderly Subjects. A Randomized Controlled Trial

Effect Increase
Trial Design Double blind
Trial Length 6+ Months
Number of Subjects 88
Sex Both Genders
Age Range 65+
Notes for this study:
In otherwise healthy older adults given vitamin E supplementation at three doses (60, 200, and 800mg) for approximately eight months who received vaccinations, it appeared that while vitamin E did not influence the overall count of B and T cells that it increased the antibody response to hepatitis B and tetanus (but not diptheria) and immunity as assessed by DTH reactivity; the effect was most effective at 200mg (65% increase in DTH reactivity) with some but lesser effects seen at both 60mg (41%) and 800mg (49%) relative to placebo (17%).

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