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| Effect | Increase |
| Trial Design | Double blind |
| Trial Length | 6+ Months |
| Number of Subjects | 88 |
| Sex | Both Genders |
| Age Range | 65+ |
In otherwise healthy older adults given vitamin E supplementation at three doses (60, 200, and 800mg) for approximately eight months who received vaccinations, it appeared that while vitamin E did not influence the overall count of B and T cells that it increased the antibody response to hepatitis B and tetanus (but not diptheria) and immunity as assessed by DTH reactivity; the effect was most effective at 200mg (65% increase in DTH reactivity) with some but lesser effects seen at both 60mg (41%) and 800mg (49%) relative to placebo (17%).
