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Vitamin E Supplementation Enhances Cell-mediated Immunity In Healthy Elderly Subjects
| Effect | None |
| Trial Design | Double blind |
| Trial Length | 2-4 Weeks |
| Number of Subjects | 32 |
| Sex | Both Genders |
| Age Range | 65+ |
30 days supplementation of vitamin E as alpha-tocopherol (800mg) to otherwise healthy older adults appeared to increase immunity (DTH reactivity) and IL-2 concentrations and the mitogenic response to a mitogen (concavalin A) by 67+/-24% and 24% respectively.
These changes were associated with a reduction in PGE2 secretion from immune cells and a decrease in lipid peroxidation in plasma.
