Randomized Trial Of Vitamin D Supplementation To Prevent Seasonal Influenza A In Schoolchildren
| Effect | None |
| Values | Cases and percentage. Placebo: 2/167 (1.2). Vitamin D: 2/167 (1.2) |
| Trial Design | Randomized trial |
| Trial Length | 1-6 months |
| Number of Subjects | 334 |
| Sex | Both Genders |
| Age Range | 1-6, 7-12, 13-17 |
In a randomized, double-blind, placebo-controlled trial, 334 school children were given 1200 IU of vitamin D or placebo daily for 4 months from December to the end of March.
96 participants dropped out of the study and weren't analyzed. The primary outcome was the incidence of influenza A, and the vitamin D group had a significantly lower rate. The vitamin D group had a nonsignificantly higher rate of influenza B, asthma, and gastroenteritis, the same rate of influenza-like illness, nonspecific febrile disease, and pneumonia.
