Vitamin D Supplementation For Premenstrual Syndrome-Related Inflammation And Antioxidant Markers In Students With Vitamin D Deficient: A Randomized Clinical Trial

Effect Increase
Values (u/ml) TAC. Mean + SD. Placebo: before 19 ± 11, after 16 ± 12. Vitamin D: before 13 ± 2, after 21 ± 2.
Trial Design Randomized trial
Trial Length 1-6 months
Number of Subjects 44
Sex Female
Age Range 18-29
Notes for this study:
In a randomized, double-blind, placebo-controlled trial, 44 women with premenstrual syndrome and vitamin d deficiency (serum 25(OH)D levels 10–30 ng/mL) were allocated to take placebo or 50,000 IU of vitamin d every 2 weeks for 4 months. After 4 months, there was a greater reduction in PMS symptoms in the vitamin D group, the difference between groups being statistically significant. The vitamin D group also saw a greater reduction in IL-10, IL-12, and a greater increase in total antioxidant capacity, all of which were statistically significant compared with placebo.

Full details on all 2 studies are available to Examine Members. Try out the Examine Membership with a 14-day free trial.

Already a Member? Log in now to access.